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Precolumns and precolumn cartridges for HPLC

Separating columns with modern solid phases are critical components of HPLC analysis. Protect these valuable ingredients from contamination to ensure optimum and consistent separation. In order to prolong the "life" of your HPLC columns, it is advisable to use precolumns. Precolumns offer the advantage in HPLC that they also retain molecules which would form an irreversible bond with the column material. The precolumns should be exchanged regularly. A good indication of the time of the exchange is a gradual increase in the back pressure: For more information, see the care and maintenance of HPLC columns. We carry a wide range of the best manufacturers of solid phase and stainless steel cartridges for HPLC and UHPLC.

For more Information about the guard columns, please click here.

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Guard Columns

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  1. Agilent Technologies

    Eclipse XDB-C18 4.6x12.5,5u Grd Car 4/PK

    €205.00
    SKU: AG820950-925
    In Stock
  2. Agilent Technologies

    HPLC column Hochleist. Zorbax Guardn-Fittings-Kit

    €228.00
    SKU: AG820999-901
    In Stock
  3. Agilent Technologies

    ChromGuard R 10 x 3.0mm Repl5

    €305.00
    SKU: AGCP28186
    In Stock
  4. Macherey-Nagel

    EC 4/3 NUCLEOSIL 100-5 C18

    €108.00
    SKU: MN721074.30
    In Stock
  5. Merck Millipore

    Chromolith RP-18 endcapped 5 - 4.6 mm guard column kit

    €339.00
    SKU: MC1514700001
    In Stock
  6. Nacalai Tesque

    COSMOSIL 5C18-MS-II Guard Column, 4.6mmI.D. x 10mm

    €184.80
    SKU: CO-38014-31
    In Stock
  7. Waters

    VanGuard Cartridge Holder

    €153.00
    SKU: WT186007949
    In Stock
  8. Guard Column Holder direct, 10 x 2 mm Guard Column Holder direct, 10 x 2 mm
    Sale
    Altmann Analytik

    Guard Column Holder direct, 10x2 mm

    Regular Price: €126.00

    Special Price €119.70

    SKU: AAHD-01020
    In Stock
  9. Guard Column Holder direct, 10 x 4 mm Guard Column Holder direct, 10 x 4 mm
    Sale
    Altmann Analytik

    Guard Column Holder direct, 10x4 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHD-01040
    In Stock
  10. Guard Column Holder direct, 5 x 4 mm Guard Column Holder direct, 5 x 4 mm
    Sale
    Altmann Analytik

    Guard Column Holder direct, 5x4 mm

    Regular Price: €120.00

    Special Price €114.00

    SKU: AAHD-0540
    In Stock
  11. Guard Column Holder indirect, 10 x 2 mm Guard Column Holder indirect, 10 x 2 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 10x2 mm

    Regular Price: €126.00

    Special Price €119.70

    SKU: AAHI-01020
    In Stock
  12. indirect Guard Cartridge Holder, 10x3mm indirect Guard Cartridge Holder, 10x3mm
    Sale
    Altmann Analytik

    indirect Guard Cartridge Holder, 10x3mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01030
    In Stock
  13. Guard Column Holder indirect, 10 x 4 mm Guard Column Holder indirect, 10 x 4 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 10x4 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01040
    In Stock
  14. Guard Column Holder indirect, 5 x 2 mm Guard Column Holder indirect, 5 x 2 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 5x2 mm

    Regular Price: €108.00

    Special Price €102.60

    SKU: AAHI-0520
    In Stock
  15. Guard Column Holder indirect, 5 x 4 mm Guard Column Holder indirect, 5 x 4 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 5x4 mm

    Regular Price: €120.00

    Special Price €114.00

    SKU: AAHI-0540
    In Stock
  16. Altmann Analytik

    Guard Column Cartridge Hypersil APS 5µm 10x4, 5/PAK

    €115.50
    SKU: AAVHSAPS-501040-5
    In Stock
  17. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €120.00
    SKU: AAVRP-500520-5
    In Stock
  18. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €120.00
    SKU: AAVRP-500540-5
    In Stock
  19. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €125.00
    SKU: AAVRP-501020-5
    In Stock
  20. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €125.00
    SKU: AAVRP-501040-5
    In Stock
  21. Thermo Fisher Scientific

    10x4mm, 3µ Hypersil BDS Cyano Guard 4/PAK

    €292.52
    SKU: TF28803-014001
  22. Thermo Fisher Scientific

    10x2.1mm 5µ Hypersil GOLD Amino Guard 4/PAK

    €311.48
    SKU: TF25705-012101
  23. Thermo Fisher Scientific

    10x3mm 5µ Hypersil ODS Guard 4/PAK

    €240.85
    SKU: TF30105-013001
  24. Upchurch Scientific

    Grd Col 2mm x 2cm

    €134.45
    SKU: UPC-130B
  25. Guard Column Holder indirect, 10 x 4,6 mm Guard Column Holder indirect, 10 x 4,6 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 10x4,6 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01046
  26. Macherey-Nagel

    EC 4/3 NUCLEOSIL 120-5 C18

    €108.00
    SKU: MN721070.30
  27. Macherey-Nagel

    EC 4/3 NUCLEOSIL 100-5 NH2-RP

    €108.00
    SKU: MN721155.30
  28. Macherey-Nagel

    EC 4/3 NUCLEOSIL 100-5 C8

    €108.00
    SKU: MN721194.30
  29. Macherey-Nagel

    EC 4/3 NUCLEOSIL 100-5

    €108.00
    SKU: MN721518.30
  30. Macherey-Nagel

    EC 4/3 UNIVERSAL RP, 9 pcs.

    €260.00
    SKU: MN728778.30
  31. Macherey-Nagel

    EC 4/3 NUCLEODUR C18 Gravity, 3 µm

    €108.00
    SKU: MN761902.30
  32. Macherey-Nagel

    EC 4/2 NUCLEODUR C18 Pyramid, 3 µm

    €108.00
    SKU: MN761916.20
  33. Macherey-Nagel

    EC 4/3 NUCLEODUR C18 Pyramid, 5 µm

    €108.00
    SKU: MN761917.30
  34. Macherey-Nagel

    EC 4/2 NUCLEODUR 100-5 C18 ec

    €108.00
    SKU: MN761932.20
  35. Macherey-Nagel

    EC 4/3 NUCLEODUR C18 PAH, 3 µm

    €109.00
    SKU: MN761971.30
  36. Merck Millipore

    LiChroCART 4-4 ChiraDex HPLC guard cartridge

    €259.00
    SKU: MC1501170001
  37. Merck Millipore

    LiChroCART 4-4 LiChrospher® Si 60 (5 µm) HPLC guard column

    €331.00
    SKU: MC1509550001
  38. Merck Millipore

    Chromolith SemiPrep RP18e 10-10 MM Guard cartridge

    €522.00
    SKU: MC1520360001
  39. Restek

    Rxi Guard Column 5m, 0.25mm ID

    €71.00
    SKU: RE10029
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Consistent resolution in RP Chromatography

It makes sense to ensure consistent resolution in reverse-phase (RP) chromatography by removing non-polar contaminants, particularly in diagnostics applications and food analysis. With our large selection of stainless steel guard columns and stationary phases, we can meet your needs for HPLC hardware and consumables.

Whenever consistent resolution and reproducibility are required, e.g. in samples from biological matrices, our customers can select from a wide variety of bonded solid phases. From food analysis to forensic toxicology, the routine for every chromatographic method is to use column guards to protect your investment and to ensure consistent operations at only a fraction of the cost for a new HPLC or UHPLC column.

When using HPLC guard columns to protect the columns, a column holder is required. The following diagrams show you the connection possibilities when you need a precolumn to an HPLC column (column connectors have to be ordered separately):

Wide range of manufacturers: from Agilent to Waters

We offer all the trusted brands, such as Advanced Materials Technology, Agilent Technologies, Chiral, Merck, Thermo Fisher Scientifc, Waters and Whatman. As a cost-effective alternative, we carry a large selection of our own high quality brand Altmann Analytik.

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