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Precolumns and precolumn cartridges for HPLC

Separating columns with modern solid phases are critical components of HPLC analysis. Protect these valuable ingredients from contamination to ensure optimum and consistent separation. In order to prolong the "life" of your HPLC columns, it is advisable to use precolumns. Precolumns offer the advantage in HPLC that they also retain molecules which would form an irreversible bond with the column material. The precolumns should be exchanged regularly. A good indication of the time of the exchange is a gradual increase in the back pressure: For more information, see the care and maintenance of HPLC columns. We carry a wide range of the best manufacturers of solid phase and stainless steel cartridges for HPLC and UHPLC.

For more Information about the guard columns, please click here.

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Guard Columns

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  1. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €125.00
    SKU: AAVRP-501040-5
    In Stock
  2. Agilent Technologies

    SB-C18 Guard Cartridges 4.6x12.54/PK

    €205.00
    SKU: AG820950-920
  3. Agilent Technologies

    HPLC column Hochleist. Zorbax Guardn-Fittings-Kit

    €228.00
    SKU: AG820999-901
    In Stock
  4. Agilent Technologies

    ChromGuard R 10 x 3.0mm Repl5

    €305.00
    SKU: AGCP28186
    In Stock
  5. Macherey-Nagel

    EC 4/3 NUCLEOSIL 100-5 C18

    €108.00
    SKU: MN721074.30
    In Stock
  6. Macherey-Nagel

    EC 4/3 NUCLEOSIL 100-3 C18 NAUTILUS

    €108.00
    SKU: MN721649.30
  7. Merck Millipore

    Chromolith RP-18 endcapped 5 - 4.6 mm guard column kit

    €339.00
    SKU: MC1514700001
    In Stock
  8. Nacalai Tesque

    COSMOSIL 5C18-MS-II Guard Column, 4.6mmI.D. x 10mm

    €184.80
    SKU: CO-38014-31
    In Stock
  9. Thermo Fisher Scientific

    10x2.1mm 5µ Hypercarb Guard 2/PAK

    €314.48
    SKU: TF35005-012101
  10. Waters

    VanGuard Cartridge Holder

    €153.00
    SKU: WT186007949
    In Stock
  11. Guard Column Holder direct, 10 x 2 mm Guard Column Holder direct, 10 x 2 mm
    Sale
    Altmann Analytik

    Guard Column Holder direct, 10x2 mm

    Regular Price: €126.00

    Special Price €119.70

    SKU: AAHD-01020
  12. Guard Column Holder direct, 10 x 4 mm Guard Column Holder direct, 10 x 4 mm
    Sale
    Altmann Analytik

    Guard Column Holder direct, 10x4 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHD-01040
    In Stock
  13. Guard Column Holder direct, 5 x 4 mm Guard Column Holder direct, 5 x 4 mm
    Sale
    Altmann Analytik

    Guard Column Holder direct, 5x4 mm

    Regular Price: €120.00

    Special Price €114.00

    SKU: AAHD-0540
    In Stock
  14. Guard Column Holder indirect, 10 x 2 mm Guard Column Holder indirect, 10 x 2 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 10x2 mm

    Regular Price: €126.00

    Special Price €119.70

    SKU: AAHI-01020
    In Stock
  15. indirect Guard Cartridge Holder, 10x3mm indirect Guard Cartridge Holder, 10x3mm
    Sale
    Altmann Analytik

    indirect Guard Cartridge Holder, 10x3mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01030
    In Stock
  16. Guard Column Holder indirect, 10 x 4 mm Guard Column Holder indirect, 10 x 4 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 10x4 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01040
    In Stock
  17. Guard Column Holder indirect, 5 x 2 mm Guard Column Holder indirect, 5 x 2 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 5x2 mm

    Regular Price: €108.00

    Special Price €102.60

    SKU: AAHI-0520
    In Stock
  18. Guard Column Holder indirect, 5 x 4 mm Guard Column Holder indirect, 5 x 4 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 5x4 mm

    Regular Price: €120.00

    Special Price €114.00

    SKU: AAHI-0540
    In Stock
  19. Altmann Analytik

    Guard Column Cartridge Hypersil APS 5µm 10x4, 5/PAK

    €115.50
    SKU: AAVHSAPS-501040-5
    In Stock
  20. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €120.00
    SKU: AAVRP-500520-5
    In Stock
  21. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €120.00
    SKU: AAVRP-500540-5
    In Stock
  22. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €125.00
    SKU: AAVRP-501020-5
    In Stock
  23. Thermo Fisher Scientific

    10x4mm, 3µ Hypersil BDS Cyano Guard 4/PAK

    €292.52
    SKU: TF28803-014001
  24. HPLC Guard Cartridge CORTECS C18, 90Å, 2.7 µm, 2.1 mm X 5 mm, 3/PK HPLC Guard Cartridge CORTECS C18, 90Å, 2.7 µm, 2.1 mm X 5 mm, 3/PK
    Sale
    Waters

    HPLC Guard Cartridge CORTECS C18, 90Å, 2.7 µm, 2.1 mm X 5 mm, 3/PK

    Regular Price: €400.00

    Special Price €360.00

    SKU: WT186007682
  25. HPLC Guard Cartridge CORTECS C18, 90Å, 2.7 µm, 3.9 mm X 5 mm, 3/PK HPLC Guard Cartridge CORTECS C18, 90Å, 2.7 µm, 3.9 mm X 5 mm, 3/PK
    Sale
    Waters

    HPLC Guard Cartridge CORTECS C18, 90Å, 2.7 µm, 3.9 mm X 5 mm, 3/PK

    Regular Price: €400.00

    Special Price €360.00

    SKU: WT186007684
  26. HPLC Guard Cartridge CORTECS C18+, 90Å, 2.7 µm, 2.1 mm X 5 mm, 3/PK HPLC Guard Cartridge CORTECS C18+, 90Å, 2.7 µm, 2.1 mm X 5 mm, 3/PK
    Sale
    Waters

    HPLC Guard Cartridge CORTECS C18+, 90Å, 2.7 µm, 2.1 mm X 5 mm, 3/PK

    Regular Price: €400.00

    Special Price €360.00

    SKU: WT186007685
  27. HPLC Guard Cartridge XSelect CSH Fluoro Phenyl XP, 130Å, 2.5 µm, 3.9 mm X 5 mm, 3/PK HPLC Guard Cartridge XSelect CSH Fluoro Phenyl XP, 130Å, 2.5 µm, 3.9 mm X 5 mm, 3/PK
    Sale
    Waters

    HPLC Guard Cartridge XSelect CSH Fluoro Phenyl XP, 130Å, 2.5 µm, 3.9 mm X 5 mm, 3/PK

    Regular Price: €406.00

    Special Price €365.40

    SKU: WT186007829
  28. Thermo Fisher Scientific

    10x2.1mm 5µ Hypersil GOLD Amino Guard 4/PAK

    €311.48
    SKU: TF25705-012101
  29. Thermo Fisher Scientific

    10x3mm 5µ Hypersil ODS Guard 4/PAK

    €240.85
    SKU: TF30105-013001
  30. Upchurch Scientific

    Grd Col 2mm x 2cm

    €134.45
    SKU: UPC-130B
  31. Guard Column Holder indirect, 10 x 4,6 mm Guard Column Holder indirect, 10 x 4,6 mm
    Sale
    Altmann Analytik

    Guard Column Holder indirect, 10x4,6 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01046
  32. Macherey-Nagel

    EC 4/3 NUCLEOSIL 120-5 C18

    €108.00
    SKU: MN721070.30
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Consistent resolution in RP Chromatography

It makes sense to ensure consistent resolution in reverse-phase (RP) chromatography by removing non-polar contaminants, particularly in diagnostics applications and food analysis. With our large selection of stainless steel guard columns and stationary phases, we can meet your needs for HPLC hardware and consumables.

Whenever consistent resolution and reproducibility are required, e.g. in samples from biological matrices, our customers can select from a wide variety of bonded solid phases. From food analysis to forensic toxicology, the routine for every chromatographic method is to use column guards to protect your investment and to ensure consistent operations at only a fraction of the cost for a new HPLC or UHPLC column.

When using HPLC guard columns to protect the columns, a column holder is required. The following diagrams show you the connection possibilities when you need a precolumn to an HPLC column (column connectors have to be ordered separately):

Wide range of manufacturers: from Agilent to Waters

We offer all the trusted brands, such as Advanced Materials Technology, Agilent Technologies, Chiral, Merck, Thermo Fisher Scientifc, Waters and Whatman. As a cost-effective alternative, we carry a large selection of our own high quality brand Altmann Analytik.

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