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Precolumns (guard columns) and precolumn cartridges for HPLC

Separation columns with modern solid phases are critical components of the HPLC system. Careful handling and protection against impurities is necessary to ensure optimum and consistent separation results. In order to extend the life of your HPLC columns, it is advisable to use guard columns. They are able to remove molecules which would form an irreversible bond with the material of the analytical column. Guard coloumns need to be changed on a regular basis. A good indication on when to change a precolumn is a gradual increase in the back pressure. For more information on the storage and maintenance of HPLC column, click here.

We offer a wide range of HPLC and UHPLC precolumns and stainless steel cartridges from the most established manufacturers in our shop.

Click here for more Information on guard columns.

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Guard Columns

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  1. Waters

    HPLC VanGuard Cartridge Holder

    €165.00
    SKU: WT186007949
    In Stock
  2. Macherey-Nagel

    Column Protection System Guard Column Holder

    €134.20
    SKU: MN718966
    In Stock
  3. Chiral

    GUARD CARTRIDGE HOLDER FOR HPLC COLUMNS

    €149.00
    SKU: DAIC00081
    In Stock
  4. Macherey-Nagel

    VP Guard column holder 8 mm

    €207.90
    SKU: MN718251
    In Stock
  5. Macherey-Nagel

    VP Guard column holder 32 mm (short)

    €404.80
    SKU: MN718253
    In Stock
  6. Waters

    HPLC Guard Cartridge XTerra MS C18 125Å 5 µm 10 mm X 10 mm

    €265.00
    SKU: WT186001001
    In Stock
  7. Waters

    HPLC Guard Cartridge XTerra RP 8 125Å 5 µm 10 mm X 10 mm

    €265.00
    SKU: WT186001008
    In Stock
  8. Waters

    HPLC Guard Cartridge XTerra RP 8 125Å 10 µm 10 mm X 10 mm

    €255.00
    SKU: WT186001009
    In Stock
  9. Waters

    HPLC Guard Cartridge XTerra MS C8 125Å 10 µm 19 mm X 10 mm

    €440.00
    SKU: WT186001035
    In Stock
  10. Waters

    HPLC Guard Cartridge XTerra RP 8 125Å 10 µm 19 mm X 10 mm

    €440.00
    SKU: WT186001037
    In Stock
  11. Waters

    HPLC Guard Cartridge XTerra MS C18 125Å 5 µm 19 mm X 10 mm

    €445.00
    SKU: WT186001104
    In Stock
  12. Waters

    HPLC Guard Cartridge XTerra MS C8 125Å 5 µm 19 mm X 10 mm

    €445.00
    SKU: WT186001105
    In Stock
  13. Waters

    HPLC Guard Cartridge XTerra RP 8 125Å 5 µm 19 mm X 10 mm

    €445.00
    SKU: WT186001107
    In Stock
  14. Waters

    HPLC Guard Cartridge XTerra MS C8 125Å 5 µm 7.8 mm X 10 mm

    €265.00
    SKU: WT186001169
    In Stock
  15. Waters

    HPLC Guard Cartridge XTerra RP 8 125Å 5 µm 7.8 mm X 10 mm

    €265.00
    SKU: WT186001171
    In Stock
  16. Waters

    HPLC Guard Cartridge XTerra RP 8 125Å 10 µm 7.8 mm X 10 mm

    €230.00
    SKU: WT186001175
    In Stock
  17. Waters

    HPLC Guard Cartridge Symmetry C18 300Å 5 µm 19 mm X 10 mm

    €455.00
    SKU: WT186001847
    In Stock
  18. Waters

    HPLC Guard Column Envirogel GPC Cleanup, 15 µm, 4.6x30 mm

    €425.00
    SKU: WT186001914
    In Stock
  19. Waters

    HPLC Guard Cartridge SunFire C18 100Å 10 µm 10 mm X 10 mm

    €255.00
    SKU: WT186002663
    In Stock
  20. Waters

    HPLC Guard Cartridge SunFire C18 100Å 10 µm 19 mm X 10 mm

    €440.00
    SKU: WT186002666
    In Stock
  21. Waters

    HPLC Guard Column HSS T3 5µm 4.6x50mm

    €650.00
    SKU: WT186004794
    In Stock
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Consistent resolution in RP Chromatography

It makes sense to ensure consistent resolution in reverse-phase (RP) chromatography by removing non-polar contaminants, particularly in diagnostics applications and food analysis. With our large selection of stainless steel guard columns and stationary phases, we can meet your needs for HPLC hardware and consumables.

Whenever consistent resolution and reproducibility are required, e.g. in samples from biological matrices, our customers can select from a wide variety of bonded solid phases. From food analysis to forensic toxicology, the routine for every chromatographic method is to use column guards to protect your investment and to ensure consistent operations at only a fraction of the cost for a new HPLC or UHPLC column.

When using HPLC guard columns to protect the columns, a column holder is required. The following diagrams show you the connection possibilities when you need a precolumn to an HPLC column (column connectors have to be ordered separately):

Wide range of manufacturers: from Agilent to Waters

Products of all trusted brands such as Advanced Materials Technology, Agilent Technologies, Chiral, Merck, Thermo Fisher Scientifc, Waters and Whatman are available in our shop. As a cost-effective alternative, check out our own high quality products from Altmann Analytik.

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