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Precolumns and precolumn cartridges for HPLC

Separating columns with modern solid phases are critical components of HPLC analysis. Protect these valuable ingredients from contamination to ensure optimum and consistent separation. In order to prolong the "life" of your HPLC columns, it is advisable to use precolumns. Precolumns offer the advantage in HPLC that they also retain molecules which would form an irreversible bond with the column material. The precolumns should be exchanged regularly. A good indication of the time of the exchange is a gradual increase in the back pressure: For more information, see the care and maintenance of HPLC columns. We carry a wide range of the best manufacturers of solid phase and stainless steel cartridges for HPLC and UHPLC.

For more Information about the guard columns, please click here.

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Guard Columns

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  1. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €125.00
    SKU: AAVRP-501040-5
    In Stock
  2. Chiral

    GUARD CARTRIDGE HOLDER FOR HPLC COLUMNS

    €145.00
    SKU: DAIC00081
  3. PerkinElmer

    Brownlee NewGuard/CHOICE Holder

    €303.00
    SKU: PE07150001
    In Stock
  4. Waters

    SENTRY GUARD HOLDER UNIVERSAL

    €182.00
    SKU: WTWAT046910
    In Stock
  5. Thermo Fisher Scientific

    UNIGUARD Drop-in Holder, 4.6/4.0mm

    €118.42
    SKU: TF850-00
    In Stock
  6. Chiral

    Chiral Technologies GUARD CARTRIDGE HOLDER

    €172.00
    SKU: DAIC00011
    In Stock
  7. Macherey-Nagel

    Column Protection System Guard Column Holder

    Regular Price: €122.00

    Special Price €109.80

    SKU: MN718966
    In Stock
  8. Imtakt

    Guard Holder

    €292.00
    SKU: ITGCH01S
    In Stock
  9. Altmann Analytik

    Guard Column Holder direct, 5 x 2 mm

    Regular Price: €108.00

    Special Price €102.60

    SKU: AAHD-0520
  10. Altmann Analytik

    Guard Column Holder direct, 5 x 4 mm

    Regular Price: €120.00

    Special Price €114.00

    SKU: AAHD-0540
    In Stock
  11. Altmann Analytik

    Guard Column Holder indirect, 10 x 2 mm

    Regular Price: €126.00

    Special Price €119.70

    SKU: AAHI-01020
  12. Altmann Analytik

    indirect Guard Cartridge Holder, 10x3mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01030
    In Stock
  13. Altmann Analytik

    Guard Column Holder indirect, 5 x 2 mm

    Regular Price: €108.00

    Special Price €102.60

    SKU: AAHI-0520
  14. Altmann Analytik

    Guard Column Holder indirect, 5 x 4 mm

    Regular Price: €120.00

    Special Price €114.00

    SKU: AAHI-0540
    In Stock
  15. Agilent Technologies

    HPLC Guard Cartridge Eclipse x DB-C18 4.6 x 12.5,5µm, 4 pcs.

    €213.00
    SKU: AG820950-925
    In Stock
  16. Agilent Technologies

    HPLC Column Hochleist. Zorba x Guardn-Fittings-Kit

    €236.00
    SKU: AG820999-901
    In Stock
  17. Agilent Technologies

    HPLC ChromGuard Column R 10 x 3.0 mm Repl5

    €325.00
    SKU: AGCP28186
    In Stock
  18. Macherey-Nagel

    EC 4/3 NUCLEOSIL 100-5 C18

    €111.00
    SKU: MN721074.30
    In Stock
  19. Macherey-Nagel

    EC 4/3 NUCLEODUR C18 Pyramid, 3 µm

    €111.00
    SKU: MN761916.30
  20. Macherey-Nagel

    EC 4/3 NUCLEODUR 100-3 C18 ec

    €111.00
    SKU: MN761931.30
  21. Macherey-Nagel

    EC 4/3 NUCLEODUR 100-3 NH2-RP

    €111.00
    SKU: MN761951.30
  22. Nacalai Tesque

    COSMOSIL 5C18-MS-II Guard Column, 4.6mmI.D. x 10mm

    €187.95
    SKU: CO-38014-31
    In Stock
  23. Waters

    HPLC Guard Cartridge Symmetry C18 100Å 7 µm 7.8 mm X 10 mm

    €244.00
    SKU: WT186000713
    In Stock
  24. Altmann Analytik

    Guard Column Cartridge Hypersil APS 5µm 10 x 4, 5/PAK

    €115.50
    SKU: AAVHSAPS-501040-5
    In Stock
  25. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €120.00
    SKU: AAVRP-500520-5
    In Stock
  26. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €120.00
    SKU: AAVRP-500540-5
    In Stock
  27. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €125.00
    SKU: AAVRP-501020-5
    In Stock
  28. Altmann Analytik

    Universal Reversed Phase (RP) pre-column cartridge

    €115.00
    SKU: AAVRP-201040-5
    In Stock
  29. Waters

    HPLC VanGuard Cartridge Holder

    €158.00
    SKU: WT186007949
    In Stock
  30. Imtakt

    Cadenza CW-C18 Guard Cartridge (5x2mm), 3pcs

    €227.00
    SKU: ITGCCW0S
    In Stock
  31. Waters

    HPLC Cartridge CORTECS C18 90Å, 2.7 µm, 2.1x5 mm, 3/PAK

    Regular Price: €408.00

    Special Price €367.20

    SKU: WT186007682
  32. Waters

    HPLC Cartridge CORTECS C18 90Å, 2.7 µm, 3.9x5 mm, 3/PAK

    Regular Price: €408.00

    Special Price €367.20

    SKU: WT186007684
  33. Waters

    HPLC Cartridge CORTECS C18+ 90Å, 2.7 µm, 2.1x5 mm, 3/PAK

    Regular Price: €408.00

    Special Price €367.20

    SKU: WT186007685
  34. Waters

    HPLC Cartridge XSelect CSH Fluoro Phenyl XP 130Å, 2.5 µm, 3.9x5 mm, 3/PAK

    Regular Price: €415.00

    Special Price €373.50

    SKU: WT186007829
  35. Altmann Analytik

    Guard Column Holder direct, 10 x 2 mm

    Regular Price: €126.00

    Special Price €119.70

    SKU: AAHD-01020
  36. Altmann Analytik

    Guard Column Holder direct, 10 x 4 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHD-01040
  37. Altmann Analytik

    Guard Column Holder direct, 5 x 4,6 mm

    Regular Price: €72.00

    Special Price €68.40

    SKU: AAHD-0546
  38. Altmann Analytik

    Guard Column Holder indirect, 10 x 4 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01040
  39. Altmann Analytik

    Guard Column Holder indirect, 10 x 4,6 mm

    Regular Price: €132.00

    Special Price €125.40

    SKU: AAHI-01046
  40. Merck

    LiChroCART 4-4 ChiraDex HPLC guard cartridge

    €265.00
    SKU: MC1501170001
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Consistent resolution in RP Chromatography

It makes sense to ensure consistent resolution in reverse-phase (RP) chromatography by removing non-polar contaminants, particularly in diagnostics applications and food analysis. With our large selection of stainless steel guard columns and stationary phases, we can meet your needs for HPLC hardware and consumables.

Whenever consistent resolution and reproducibility are required, e.g. in samples from biological matrices, our customers can select from a wide variety of bonded solid phases. From food analysis to forensic toxicology, the routine for every chromatographic method is to use column guards to protect your investment and to ensure consistent operations at only a fraction of the cost for a new HPLC or UHPLC column.

When using HPLC guard columns to protect the columns, a column holder is required. The following diagrams show you the connection possibilities when you need a precolumn to an HPLC column (column connectors have to be ordered separately):

Wide range of manufacturers: from Agilent to Waters

We offer all the trusted brands, such as Advanced Materials Technology, Agilent Technologies, Chiral, Merck, Thermo Fisher Scientifc, Waters and Whatman. As a cost-effective alternative, we carry a large selection of our own high quality brand Altmann Analytik.

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