Merck HPLC Columns

Merck HPLC Columns

Merck is one of the major producers of HPLC columns world wide. As an official distributor we can offer more than 1,000 different HPLC columns by Merck for every analytical or preparative problem.

Merck HPLC columns are available in different configurations:

Phase: LiChrosorbLiChrospherZIC-HILICSuperspherChromolith, etc.

Packing: Amino, CN, Diol, Phenyl, C18, C8, etc.

Pore Size: 60 Å, 100 Å, 200 Å, etc.

If you have any questions concerning Merck HPLC columns, please use our HPLC column configurator or contact us personally.

Sort By

Items 1-50 of 546

per page
Product Image of HPLC Column Hibar 250x4.6mm, Purospher STAR RP-18 endcapped, 5µm
HPLC Column Hibar 250x4.6mm, Purospher STAR RP-18 endcapped, 5µm
Item number: MC1514560001
Brand: Merck

In stock

€827.41 €853.00
Product Image of HPLC Guard Column Chromolith RP-18 endcapped 5x4.6mm, 3 columns, monolithic, ready-to-use
HPLC Guard Column Chromolith RP-18 endcapped 5x4.6mm, 3 columns, monolithic, ready-to-use
Item number: MC1514510001
Brand: Merck

In stock

€357.51 €368.57
Product Image of HPLC Precolumnn LiChroCART 4x4mm, LiChrospher® 100 RP-18, 5µm, 10/PAK
HPLC Precolumnn LiChroCART 4x4mm, LiChrospher® 100 RP-18, 5µm, 10/PAK
Item number: MC1509570001
Brand: Merck

In stock

€341.60 €427.00
Product Image of HPLC Cartridge LiChroCART 125x4mm, LiChrospher® 100 RP-18, 5µm
HPLC Cartridge LiChroCART 125x4mm, LiChrospher® 100 RP-18, 5µm
Item number: MC1509430001
Brand: Merck

In stock

€1,154.30 €1,190.00
Product Image of HPLC Cartridge LiChroCART 25x4mm, LiChrospher® 100 RP-18 endcapped, 5µm
HPLC Cartridge LiChroCART 25x4mm, LiChrospher® 100 RP-18 endcapped, 5µm
Item number: MC1509360001
Brand: Merck

In stock

€699.37 €721.00
Product Image of HPLC Cartridge LiChroCART 250x4mm, LiChrospher® 100 CN, 10µm
HPLC Cartridge LiChroCART 250x4mm, LiChrospher® 100 CN, 10µm
Item number: MC1508450001
Brand: Merck

In stock

€664.45 €685.00
Product Image of HPLC Column ZIC-HILIC 150x4.6mm, 3.5µm, 100Å PEEK HPLC Column SeQuant(TM)
HPLC Column ZIC-HILIC 150x4.6mm, 3.5µm, 100Å PEEK HPLC Column SeQuant(TM)
Item number: MC1504440001
Brand: Merck

In stock

€1,241.60 €1,280.00
Product Image of HPLC Cartridge LiChroCART 250x4mm, Superspher® 60 RP-8 endcapped
HPLC Cartridge LiChroCART 250x4mm, Superspher® 60 RP-8 endcapped
Item number: MC1168570001
Brand: Merck

In stock

€748.80 €936.00
Product Image of HPLC Column Chromolith Performance RP-18 endcapped 100x4.6mm, monolithic ready-to-use HPLC Column
HPLC Column Chromolith Performance RP-18 endcapped 100x4.6mm, monolithic ready-to-use HPLC Column
Item number: MC1021290001
Brand: Merck

In stock

€963.21 €993.00
Product Image of HPLC-Scout Column Hibar RT 250x4.6mm,mm, PharmPrep P 100 RP18E, 20µm, 4.6x250mm, 1 pc
HPLC-Scout Column Hibar RT 250x4.6mm,mm, PharmPrep P 100 RP18E, 20µm, 4.6x250mm, 1 pc
Item number: MC1205720001
Brand: Merck
€679.00 €700.00
Product Image of HPLC-Scout Column Hibar RT 250x4.6mm,mm, PharmPrep P 100 RP18E, 10µm, 4.6x250mm, 1 pc
HPLC-Scout Column Hibar RT 250x4.6mm,mm, PharmPrep P 100 RP18E, 10µm, 4.6x250mm, 1 pc
Item number: MC1205710001
Brand: Merck
€711.01 €733.00
Product Image of HPLC Cartridge LiChroCART 125x2mm for Customer filling, please specify packing material, 1 pc, customized packing
HPLC Cartridge LiChroCART 125x2mm for Customer filling, please specify packing material, 1 pc, customized packing
Item number: MC1501957140
Brand: Merck
€1,015.73 €1,047.14
Product Image of HPLC Cartridge LiChroCART 125x2mm for Customer filling, please specify packing material, 1 pc, customized packing
HPLC Cartridge LiChroCART 125x2mm for Customer filling, please specify packing material, 1 pc, customized packing
Item number: MC1501957139
Brand: Merck
€1,244.37 €1,282.86
Product Image of HPLC Cartridge LiChroCART 125x2mm for Customer filling, please specify packing material, 1 pc, customized packing
HPLC Cartridge LiChroCART 125x2mm for Customer filling, please specify packing material, 1 pc, customized packing
Item number: MC1501957109
Brand: Merck
€982.47 €1,012.86
Product Image of HPLC Cartridge LiChroCART 125x2mm for Customer filling, please specify packing material, 1 pc, customized packing
HPLC Cartridge LiChroCART 125x2mm for Customer filling, please specify packing material, 1 pc, customized packing
Item number: MC1501957093
Brand: Merck
€1,078.09 €1,111.43
Product Image of HPLC Cartridge Purospher STAR RP18E, 3µm, LiChroCART 30x4mm, 3 pc
HPLC Cartridge Purospher STAR RP18E, 3µm, LiChroCART 30x4mm, 3 pc
Item number: MC1502250001
Brand: Merck
€1,276.24 €1,315.71
Product Image of HPLC Column prep Hibar 250x2mm,5 PharmPrep P 100 RP18E, 20µm, 25x250mm, 1 pc
HPLC Column prep Hibar 250x2mm,5 PharmPrep P 100 RP18E, 20µm, 25x250mm, 1 pc
Item number: MC1205740001
Brand: Merck
€5,570.57 €5,742.86
Product Image of HPLC Column prep Hibar 250x2mm,5 LiChrospher Si 60, 5µm, 25x250mm, 1 pc
HPLC Column prep Hibar 250x2mm,5 LiChrospher Si 60, 5µm, 25x250mm, 1 pc
Item number: MC1514850001
Brand: Merck
€5,930.86 €6,114.29
Product Image of HPLC Column prep Hibar 250x2mm,5 LiChrospher 100 RP8, 5µm, 25x250mm, 1 pc
HPLC Column prep Hibar 250x2mm,5 LiChrospher 100 RP8, 5µm, 25x250mm, 1 pc
Item number: MC1514820001
Brand: Merck
€11,016.43 €11,357.14
Product Image of HPLC Column prep Hibar 250x2mm,5 LiChrospher 100 RP18e, 5µm, 25x250mm, 1 pc
HPLC Column prep Hibar 250x2mm,5 LiChrospher 100 RP18e, 5µm, 25x250mm, 1 pc
Item number: MC1514780001
Brand: Merck
€7,496.71 €7,728.57
Product Image of HPLC Column Hibar RT150x4.6mm Purospher Star RP18, 5µm, 1 pc
HPLC Column Hibar RT150x4.6mm Purospher Star RP18, 5µm, 1 pc
Item number: MC1514550005
Brand: Merck
€22,781.14 €23,485.71
Product Image of HPLC Column Chromolith DIOL 5-4.6 guard Columns
HPLC Column Chromolith DIOL 5-4.6 guard Columns
Item number: MC1531750001
Brand: Merck
€357.51 €368.57
Product Image of HPLC Column Chromolith Performance DIOL 100x4.6mm
HPLC Column Chromolith Performance DIOL 100x4.6mm
Item number: MC1531720001
Brand: Merck
€1,285.94 €1,325.71
Product Image of HPLC Column Chromolith SpeedROD DIOL 50x4.6mm
HPLC Column Chromolith SpeedROD DIOL 50x4.6mm
Item number: MC1531710001
Brand: Merck
€902.10 €930.00
Product Image of HPLC Guard Cartridge Chromolith WP 300 RP-18, 5x4.6mm, 3/pk
HPLC Guard Cartridge Chromolith WP 300 RP-18, 5x4.6mm, 3/pk
Item number: MC1522730001
Brand: Merck
€357.51 €368.57
Product Image of HPLC Guard Cartridge Chromolith WP 300 RP-18, 10x4.6mm, 3/pk
HPLC Guard Cartridge Chromolith WP 300 RP-18, 10x4.6mm, 3/pk
Item number: MC1522720001
Brand: Merck
€519.64 €535.71
Product Image of HPLC Column Chromolith WP 300 RP-18, 100x4.6mm
HPLC Column Chromolith WP 300 RP-18, 100x4.6mm
Item number: MC1522710001
Brand: Merck
€1,040.67 €1,072.86
Product Image of HPLC Column Chromolith WP 300 RP-18, 100x4.6mm
HPLC Column Chromolith WP 300 RP-18, 100x4.6mm
Item number: MC1522700001
Brand: Merck
€1,482.71 €1,528.57
Product Image of HPLC Guard Cartridge Chromolith WP 300 RP-8, 5x4.6mm, 3/pk
HPLC Guard Cartridge Chromolith WP 300 RP-8, 5x4.6mm, 3/pk
Item number: MC1522680001
Brand: Merck
€357.51 €368.57
Product Image of HPLC Guard Cartridge Chromolith WP 300 RP-8, 10x4.6mm, 3/pk
HPLC Guard Cartridge Chromolith WP 300 RP-8, 10x4.6mm, 3/pk
Item number: MC1522670001
Brand: Merck
€519.64 €535.71
Product Image of HPLC Column Chromolith WP 300 RP-8, 50x4.6mm
HPLC Column Chromolith WP 300 RP-8, 50x4.6mm
Item number: MC1522660001
Brand: Merck
€1,003.26 €1,034.29
Product Image of HPLC Column Chromolith WP 300 RP-8, 100x4.6mm
HPLC Column Chromolith WP 300 RP-8, 100x4.6mm
Item number: MC1522650001
Brand: Merck
€1,482.71 €1,528.57
Product Image of HPLC Column Chromolith WP 300 Protein A, 25x4.6mm
HPLC Column Chromolith WP 300 Protein A, 25x4.6mm
Item number: MC1522580001
Brand: Merck
€1,746.00 €1,800.00
Product Image of HPLC Guard Cartridge Chromolith WP 300 Epoxy, 5x4.6mm, 3/pk
HPLC Guard Cartridge Chromolith WP 300 Epoxy, 5x4.6mm, 3/pk
Item number: MC1522540001
Brand: Merck
€357.51 €368.57
Product Image of HPLC Guard Cartridge Chromolith WP 300 Epoxy, 10x4.6mm, 3/pk
HPLC Guard Cartridge Chromolith WP 300 Epoxy, 10x4.6mm, 3/pk
Item number: MC1522530001
Brand: Merck
€519.64 €535.71
Product Image of HPLC Column Chromolith WP 300 Epoxy, 25x4.6mm
HPLC Column Chromolith WP 300 Epoxy, 25x4.6mm
Item number: MC1522520001
Brand: Merck
€891.01 €918.57
Product Image of HPLC Column Chromolith WP 300 Epoxy, 50x4.6mm
HPLC Column Chromolith WP 300 Epoxy, 50x4.6mm
Item number: MC1522510001
Brand: Merck
€1,040.67 €1,072.86
Product Image of HPLC Column Chromolith WP 300 Epoxy, 100x4.6mm
HPLC Column Chromolith WP 300 Epoxy, 100x4.6mm
Item number: MC1522500001
Brand: Merck
€1,579.71 €1,628.57
Product Image of HPLC Column Chromolith® HighResolution RP-8 endcapped 100x4.6mm, monolithic
HPLC Column Chromolith® HighResolution RP-8 endcapped 100x4.6mm, monolithic
Item number: MC1520640001
Brand: Merck
€1,285.94 €1,325.71
Product Image of HPLC Column Chromolith RP-18 endcapped 100x3mm, Validation Kit (3 Columns from 3 different batches)
HPLC Column Chromolith RP-18 endcapped 100x3mm, Validation Kit (3 Columns from 3 different batches)
Item number: MC1520630001
Brand: Merck
€4,129.43 €4,257.14
Product Image of HPLC Column Chromolith RP-18 endcapped 50x2mm, Validation Kit (3 Columns from 3 different batches)
HPLC Column Chromolith RP-18 endcapped 50x2mm, Validation Kit (3 Columns from 3 different batches)
Item number: MC1520620001
Brand: Merck
€4,129.43 €4,257.14
Product Image of HPLC Guard Cartridge Chromolith Phenyl 5-4.6 (3 pieces)
HPLC Guard Cartridge Chromolith Phenyl 5-4.6 (3 pieces)
Item number: MC1520590001
Brand: Merck
€374.14 €385.71
Product Image of HPLC Column Chromolith Phenyl 100x4.6mm
HPLC Column Chromolith Phenyl 100x4.6mm
Item number: MC1520580001
Brand: Merck
€1,285.94 €1,325.71
Product Image of HPLC Column Chromolith Phenyl 50x4.6mm
HPLC Column Chromolith Phenyl 50x4.6mm
Item number: MC1520570001
Brand: Merck
€902.10 €930.00
Product Image of HPLC Column Chromolith Phenyl 25x4.6mm
HPLC Column Chromolith Phenyl 25x4.6mm
Item number: MC1520560001
Brand: Merck
€773.23 €797.14
Product Image of HPLC Guard Cartridge Chromolith CN 5-4.6 (3 pieces)
HPLC Guard Cartridge Chromolith CN 5-4.6 (3 pieces)
Item number: MC1520500001
Brand: Merck
€374.14 €385.71
Product Image of HPLC Column Chromolith CN 100x4.6mm
HPLC Column Chromolith CN 100x4.6mm
Item number: MC1520480001
Brand: Merck
€1,285.94 €1,325.71
Product Image of HPLC Column Chromolith CN 50x4.6mm
HPLC Column Chromolith CN 50x4.6mm
Item number: MC1520470001
Brand: Merck
€902.10 €930.00
Product Image of HPLC Column Chromolith CN 25x4.6mm
HPLC Column Chromolith CN 25x4.6mm
Item number: MC1520460001
Brand: Merck
€773.23 €797.14
Product Image of HPLC Guard Cartridge Chromolith SemiPrep RP18e 10x10mm
HPLC Guard Cartridge Chromolith SemiPrep RP18e 10x10mm
Item number: MC1520360001
Brand: Merck
€1,019.89 €1,051.43

Merck Chromolith HPLC columns

Merck Chromolith HPLC columns are made from highly porous monolithic rods of silica with a bimodal pore structure. The column is no longer packed with small particles but instead consists of a single piece of high-purity silica gel. This enables a separation speed four times faster than with a standard particulate column. Additional advantages of Chromolith columns are a longer lifetime and lower matrix sensitivity with biological samples. Multiple Chromolith columns coupled together provide separation efficiencies of 100,000 plates/column at normal pressure.

Phase
 
Particle Size
[µm] 
Pore Size
[Å] 
pH-Area
 
Carbon Load
[%] 
Endcapping
 
RP-18 endcapped monolithic 130  2 - 7.5  18 Yes
High Resolution RP-C18e monolithic 150  2 - 7.5  18  Yes 
RP-8 endcapped monolithic 130  2 - 7.5  11  Yes 
NH2 monolithic  130  2 - 7.5 
Silica monolithic  130  2 - 7.5  18 
Prep Si monolithic  130 

 

Merck Purospher columns

Besides highly efficient Chromolith columns, Merck Millipore columns are available in frequently used materials such as LiChrosorb, LiChrospher und Superspher. Further various special sorbents such as Aluspher and diverse chiral phases are available, e.g. Purospher and Purospher STAR. These columns are based on pure silicia without metal.

Phase
 
Particle Size
[µm] 
Pore Size
[Å] 
pH-Area
 
Carbon Load
[%] 
Endcapping
 
RP-18 5 90 2 - 8 17 amino
RP-18 endcapped 5 120 2 - 8 18 hydrophobic
RP-18 HC 5 90 2 - 8 18 No
STAR RP-18 endcapped 2, 3, 5 120 1.5 - 10.5 17 hydrophobic
STAR RP-8 endcapped 2, 3, 5 120 1.5 - 10.5 11.2 hydrophobic
STAR NH2 5 120 2 - 7.5 3.5
STAR Si 5 120 2 - 7.5 No 

 

Merck Superspher HPLC Columns

Superspher is a high performance spherical silica carrier with a particle size of  4µm, providing an excellent pressure / separation performance ratio. The separation peformance of Superspher columns typically is 100,000 N/m. A broad range of modifications on Superspher are available: reversed phase derivatives (RP-8, RP-18 endcapped, RP-18, RP-18 endcapped and RP-select B) and polar derivatives (Si 60). Superspher sorbents are packed in LiChroCART cartridges in different lenghts and internal diameters. To operate with LiChroCART cartridges, the cartridge holder manu-CART has to be used.

Phase
 
Particle Size
[µm] 
Pore Size
[Å] 
pH-Area
 
Carbon Load
[%] 
Endcapping
 
Si 4 60     No
RP-8 4 60   12.5 No
RP-8 endcapped 4 60   13 Yes
RP-18 4 100   21 No
RP-18 endcapped 4 100   21.6 Yes
RP-select B 4 60   11.5 No

 

Merck ZIC-HILIC and ZIC-pHILIC - for HPLC Separation of Polar Compounds

The ZIC-HILIC column is the ideal choice for separation of polar and hydrophilic compounds as it is truly orthogonal to reversed phase chromatography (RPLC) columns. Analytes such as amino acids, peptides, carbohydrates, plant extracts and various other polar compounds that usually have little or no retention and may be affected by wettability problems in RPLC, generally have strong retention on the ZIC-HILIC column.

The zwitterionic ZIC-HILIC stationary phase is attached to porous silica and is available in columns from capillary to preparative dimensions. The separation is achieved by a hydrophilic partitioning mechanism superimposed on weak electrostatic interactions. Typical eluents contain a high content of an organic solvent (e.g. acetonitrile) mixed with buffer, i.e., comparable to RPLC eluents, however, water being the strong solvent. Also, the low content of water in the eluents enables higher detection sensitivity in many LC/MS applications.