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Solvents for GC
Recent developments in residue analysis using gas chromatography (GC) techniques have further increased the sensitivity of environmental and food analyses. In addition to improvements in instruments and columns, the quality of solvents plays a crucial role in achieving reliable results in GC and GC/MS applications. Solvents for gas chromatography are obtained from special distillation cuts.
GC solvents have been developed for the analysis of low volatile substances, especially for environmental analysis, such as the detection of pesticides, preservatives or degradation intermediates. Our GC solvent product portfolio covers all gas chromatographic applications and is especially suited for the sensitive detection methods in residue and environmental analysis. We offer solvents that are specifically tailored to your individual application areas.
SupraSolv® solvents from Merck have been specially developed for sample preparation in GC. The solvents are ideal for all GC applications, including sensitive detection tasks in residue and environmental analysis.
Whether you use ECD, FID or MS, the broad portfolio of GC solvents includes specific product grades for your specific application and detection method. SupraSolv® ECD and FID grades are specifically designed and tested for ECD (electron capture detector) and FID (flame ionization detector). Typical applications are the determination of polychlorinated biphenyls (PCBs) in water and soil or pesticides in fruits and vegetables. SupraSolv® MS is intended for use in gas chromatography coupled with mass spectrometric detection, e.g. for the analysis of dioxins and furans (PCDD/PCDF) in food and water samples or the determination of PAHs (polycyclic aromatic hydrocarbons) in food.
Both SupraSolv® grades have been thoroughly tested with these specific detectors and demonstrate the highest purity and industry-leading performance. Their high quality and batch-to-batch consistency enable reliable, accurate and reproducible results without the need for costly purification and repeated analysis. This makes your work easier, more efficient and more economical.
Solvents for headspace GC analysis of solvent residues according to Ph Eur and USP
Merck's SupraSolv® headspace series includes a range of solvents specifically designed for headspace gas chromatography. Headspace GC is the preferred method for the analysis of residual solvents in active ingredients, excipients and drugs according to Ph Eur and USP.
Accurate analysis with headspace gas chromatography requires the use of very pure solvents with extremely low concentrations of the defined residual solvents. This high purity is achieved by special state-of-the-art production processes and ensured according to the relevant ICH guideline Q3C.
GC reference substances
In gas chromatography, reference substances are commonly used to identify unknown compounds. Further areas of application are as standards in quantitative analysis and for the characterization of column properties.
At Analytics-Shop, we carry a wide range of high purity reference substances for GC from Merck. Most of these reference substances are of fully synthetic origin and therefore practically free of isomers that are difficult to separate by GC. Their detection is usually above 99%, typically even above 99.5%.
The reference substances from the hydrocarbon group are packaged in pierceable ampoules. Fatty acid methyl esters and other reference substances are supplied in glass vials with screw caps.
Features and advantages
- Practically free of isomers
- High purity substances for reliable analysis
- Assay typically above 99.5