TLC Plates

Thin-Layer Chromatography (TLC) Plates

The principle of thin-layer chromatography (TLC) has been known for over 100 years. TLC is still a very common and popular separation technique for qualitative and quantitative analysis in the laboratory. Like all chromatographic methods, the aim is to separate a compound into its chemical components. The success of this method is due to its simplicity, also in terms of sample preparation, low cost, versatility, fast development time, high sensitivity and excellent reproducibility. Thin-layer chromatography is also highly efficient: Up to 70 samples can be separated simultaneously on a TLC plate. TLC is used in many industries and research areas, e.g. clinical analysis, food chemistry and pharmaceutical production.

In our Analytics Shop you will find a large selection of TLC plates for your TLC analysis. TLC plates are available in a variety of materials like aluminium oxide, cellulose, diatomaceous earth, silica gel, Sil Gel, Silica Gel, with different pore sizes and modifications.

TLC accessories from all well-known manufacturers can also be found in the Analytics Shop. Please contact us if you have any questions on our products.

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Product Image of TLC-Plates ALUGRAM SIL G/UV254, 5x10cm, 50 pc/PAK
TLC-Plates ALUGRAM SIL G/UV254, 5x10cm, 50 pc/PAK
Item number: MN818160
Brand: Macherey-Nagel

In stock

€59.00
Product Image of TLC-Plates ALUGRAM SIL G/UV254, 20x20cm, 25 pc/PAK
TLC-Plates ALUGRAM SIL G/UV254, 20x20cm, 25 pc/PAK
Item number: MN818133
Brand: Macherey-Nagel

In stock

€142.00
Product Image of TLC-Plates ALUGRAM SIL G/UV254, 4x8cm, 50 pc/PAK
TLC-Plates ALUGRAM SIL G/UV254, 4x8cm, 50 pc/PAK
Item number: MN818131
Brand: Macherey-Nagel

In stock

€38.80
Product Image of TLC silica gel 60, aluminium sheets, 5x10cm, 50 pc/PAK
TLC silica gel 60, aluminium sheets, 5x10cm, 50 pc/PAK
Item number: MC1168350001
Brand: Merck

In stock

€78.60 €131.00
Product Image of TLC silica gel 60 F254, aluminium sheets, 20x20cm, 25 pc/PAK
TLC silica gel 60 F254, aluminium sheets, 20x20cm, 25 pc/PAK
Item number: MC1055540001
Brand: Merck

In stock

€160.80 €201.00
Product Image of TLC silica gel 60 F254, aluminium sheets, 5x7.5cm, 20 pc/PAK
TLC silica gel 60 F254, aluminium sheets, 5x7.5cm, 20 pc/PAK
Item number: MC1055490001
Brand: Merck

In stock

€42.49 €43.80
Product Image of PLC silica gel 60 RP-18 F254s, 1 mm glass plates, 20x20cm, 15 pc/PAK
PLC silica gel 60 RP-18 F254s, 1 mm glass plates, 20x20cm, 15 pc/PAK
Item number: MC1054340001
Brand: Merck

In stock

€1,232.00 €1,540.00
Product Image of WEBSEAL MAT, 96 SQUAREDARK BLUE T/S 5/PK
WEBSEAL MAT, 96 SQUAREDARK BLUE T/S 5/PK
Item number: TF60180-M120
Brand: Thermo Fisher Scientific
€112.28 €124.75
Product Image of WEBSEAL MAT, 96 RD FLAT, 7MMDARK BLUE, T/S 5/PK
WEBSEAL MAT, 96 RD FLAT, 7MMDARK BLUE, T/S 5/PK
Item number: TF60180-M111
Brand: Thermo Fisher Scientific
€112.28 €124.75
Product Image of TLC-Plates Nano-ADAMANT, 0.2mm, 10x20cm, 50 pc/PAK
TLC-Plates Nano-ADAMANT, 0.2mm, 10x20cm, 50 pc/PAK
Item number: MN821150
Brand: Macherey-Nagel
€432.00
Product Image of TLC-Plates Nano-ADAMANT, 0.2mm, 10x10cm, 25 pc/PAK
TLC-Plates Nano-ADAMANT, 0.2mm, 10x10cm, 25 pc/PAK
Item number: MN821140
Brand: Macherey-Nagel
€184.00
Product Image of TLC-Plates Nano-ADAMANT UV254, 0.2mm, 10x20cm, 50 pc/PAK
TLC-Plates Nano-ADAMANT UV254, 0.2mm, 10x20cm, 50 pc/PAK
Item number: MN821120
Brand: Macherey-Nagel
€432.00
Product Image of TLC-Plates Nano-ADAMANT UV254, 0.2mm, 10x10cm, 25 pc/PAK
TLC-Plates Nano-ADAMANT UV254, 0.2mm, 10x10cm, 25 pc/PAK
Item number: MN821110
Brand: Macherey-Nagel
€184.00
Product Image of TLC-Plates ADAMANT, 0.25mm, 20x20cm, 25 pc/PAK
TLC-Plates ADAMANT, 0.25mm, 20x20cm, 25 pc/PAK
Item number: MN821060
Brand: Macherey-Nagel
€181.00
Product Image of TLC-Plates ADAMANT, 0.25mm, 10x10cm, 25 pc/PAK
TLC-Plates ADAMANT, 0.25mm, 10x10cm, 25 pc/PAK
Item number: MN821050
Brand: Macherey-Nagel
€76.70
Product Image of TLC-Plates ADAMANT, 0.25mm, 5x10cm, 200 pc/PAK
TLC-Plates ADAMANT, 0.25mm, 5x10cm, 200 pc/PAK
Item number: MN821040.200
Brand: Macherey-Nagel
€301.00
Product Image of TLC-Plates ADAMANT, 0.25mm, 5x10cm, 50 pc/PAK
TLC-Plates ADAMANT, 0.25mm, 5x10cm, 50 pc/PAK
Item number: MN821040
Brand: Macherey-Nagel
€139.00
Product Image of TLC-Plates ADAMANT UV254, 0.25mm, 20x20cm, 25 pc/PAK
TLC-Plates ADAMANT UV254, 0.25mm, 20x20cm, 25 pc/PAK
Item number: MN821030
Brand: Macherey-Nagel
€181.00
Product Image of TLC-Plates ADAMANT UV254, 0.25mm, 10x20cm, 50 pc/PAK
TLC-Plates ADAMANT UV254, 0.25mm, 10x20cm, 50 pc/PAK
Item number: MN821025
Brand: Macherey-Nagel
€203.00
Product Image of TLC-Plates ADAMANT UV254, 0.25mm, 10x10cm, 25 pc/PAK
TLC-Plates ADAMANT UV254, 0.25mm, 10x10cm, 25 pc/PAK
Item number: MN821020
Brand: Macherey-Nagel
€76.70
Product Image of TLC-Plates ADAMANT UV254, 0.25mm, 5x20cm, 100 pc/PAK
TLC-Plates ADAMANT UV254, 0.25mm, 5x20cm, 100 pc/PAK
Item number: MN821015
Brand: Macherey-Nagel
€230.00
Product Image of TLC-Plates ADAMANT UV254, 0.25mm,5x10cm, 200 pc/PAK
TLC-Plates ADAMANT UV254, 0.25mm,5x10cm, 200 pc/PAK
Item number: MN821010.200
Brand: Macherey-Nagel
€301.00
Product Image of TLC-Plates ADAMANT UV254, 0.25mm, 5x10cm, 50 pc/PAK
TLC-Plates ADAMANT UV254, 0.25mm, 5x10cm, 50 pc/PAK
Item number: MN821010
Brand: Macherey-Nagel
€139.00
Product Image of TLC-Plates ADAMANT UV254, 0.25mm, 2.5x7.5cm, 100 pc/PAK
TLC-Plates ADAMANT UV254, 0.25mm, 2.5x7.5cm, 100 pc/PAK
Item number: MN821005
Brand: Macherey-Nagel
€206.00
Product Image of TLC-Plates ALUGRAM Xtra Nano-SILGUR UV254, 10x10cm, 25 pc/PAK
TLC-Plates ALUGRAM Xtra Nano-SILGUR UV254, 10x10cm, 25 pc/PAK
Item number: MN818442
Brand: Macherey-Nagel
€230.00
Product Image of TLC-Plates ALUGRAM Xtra Nano-SILGUR, 10x10cm, 25 pc/PAK
TLC-Plates ALUGRAM Xtra Nano-SILGUR, 10x10cm, 25 pc/PAK
Item number: MN818432
Brand: Macherey-Nagel
€230.00
Product Image of TLC-Plates ALUGRAM Xtra SILGUR UV254, 20x20cm, 25 pc/PAK
TLC-Plates ALUGRAM Xtra SILGUR UV254, 20x20cm, 25 pc/PAK
Item number: MN818423
Brand: Macherey-Nagel
€149.00
Product Image of TLC-Plates ALUGRAM Xtra SILGUR UV254, 10x20cm, 20 pc/PAK
TLC-Plates ALUGRAM Xtra SILGUR UV254, 10x20cm, 20 pc/PAK
Item number: MN818422
Brand: Macherey-Nagel
€76.70
Product Image of TLC-Plates ALUGRAM Xtra SILGUR, 20x20cm, 25 pc/PAK
TLC-Plates ALUGRAM Xtra SILGUR, 20x20cm, 25 pc/PAK
Item number: MN818413
Brand: Macherey-Nagel
€149.00
Product Image of TLC-Plates ALUGRAM Xtra SILGUR, 10x20cm, 20 pc/PAK
TLC-Plates ALUGRAM Xtra SILGUR, 10x20cm, 20 pc/PAK
Item number: MN818412
Brand: Macherey-Nagel
€76.70
Product Image of TLC-Plates ALUGRAM Xtra SIL G/UV 254, 10x20cm, 20 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G/UV 254, 10x20cm, 20 pc/PAK
Item number: MN818362
Brand: Macherey-Nagel
€68.20
Product Image of TLC-Plates ALUGRAM Xtra SIL G/UV254, 5x10cm, 50 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G/UV254, 5x10cm, 50 pc/PAK
Item number: MN818360
Brand: Macherey-Nagel
€59.00
Product Image of TLC-Plates ALUGRAM Xtra Nano-SIL G/UV254, 20x20cm, 25 pc/PAK
TLC-Plates ALUGRAM Xtra Nano-SIL G/UV254, 20x20cm, 25 pc/PAK
Item number: MN818343
Brand: Macherey-Nagel
€263.00
Product Image of TLC-Plates ALUGRAM Xtra Nano-SIL G/UV254, 5x20cm, 50 pc/PAK
TLC-Plates ALUGRAM Xtra Nano-SIL G/UV254, 5x20cm, 50 pc/PAK
Item number: MN818342
Brand: Macherey-Nagel
€155.00
Product Image of TLC-Plates ALUGRAM Xtra SIL G/UV254, 20x20cm, 25 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G/UV254, 20x20cm, 25 pc/PAK
Item number: MN818333
Brand: Macherey-Nagel
€142.00
Product Image of TLC-Plates ALUGRAM Xtra SIL G/UV254, 5x20cm, 50 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G/UV254, 5x20cm, 50 pc/PAK
Item number: MN818332
Brand: Macherey-Nagel
€77.70
Product Image of TLC-Plates ALUGRAM Xtra SIL G/UV254, 4x8cm, 50 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G/UV254, 4x8cm, 50 pc/PAK
Item number: MN818331
Brand: Macherey-Nagel
€38.80
Product Image of TLC-Plates ALUGRAM Xtra SIL G/UV254, 5x7.5cm, 20 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G/UV254, 5x7.5cm, 20 pc/PAK
Item number: MN818330.20
Brand: Macherey-Nagel
€25.70
Product Image of ALUGRAM Xtra-Sheets SIL G/UV254, 2.5x7.5cm, 200 pc/PAK
ALUGRAM Xtra-Sheets SIL G/UV254, 2.5x7.5cm, 200 pc/PAK
Item number: MN818329
Brand: Macherey-Nagel
€143.00
Product Image of TLC-Plates ALUGRAM Xtra SIL G, 5x10cm, 50 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G, 5x10cm, 50 pc/PAK
Item number: MN818261
Brand: Macherey-Nagel
€59.00
Product Image of TLC-Plates ALUGRAM Xtra Nano-SIL G, 20x20cm, 25 pc/PAK
TLC-Plates ALUGRAM Xtra Nano-SIL G, 20x20cm, 25 pc/PAK
Item number: MN818241
Brand: Macherey-Nagel
€263.00
Product Image of TLC-Plates ALUGRAM Xtra Nano-SIL G, 5x20cm, 50 pc/PAK
TLC-Plates ALUGRAM Xtra Nano-SIL G, 5x20cm, 50 pc/PAK
Item number: MN818240
Brand: Macherey-Nagel
€155.00
Product Image of TLC-Plates ALUGRAM Xtra SIL G, 20x20cm, 25 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G, 20x20cm, 25 pc/PAK
Item number: MN818233
Brand: Macherey-Nagel
€142.00
Product Image of TLC-Plates ALUGRAM Xtra SIL G, 5x20cm, 50 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G, 5x20cm, 50 pc/PAK
Item number: MN818232
Brand: Macherey-Nagel
€77.70
Product Image of TLC-Plates ALUGRAM Xtra SIL G, 5x7.5cm, 20 pc/PAK
TLC-Plates ALUGRAM Xtra SIL G, 5x7.5cm, 20 pc/PAK
Item number: MN818230.20
Brand: Macherey-Nagel
€25.70
Product Image of TLC-Plates ALUGRAM NANO SIL CN/UV, 4x8cm, 50 pc/PAK
TLC-Plates ALUGRAM NANO SIL CN/UV, 4x8cm, 50 pc/PAK
Item number: MN818184
Brand: Macherey-Nagel
€206.00
Product Image of TLC-Plates ALUGRAM NANO SIL NH2/UV 4x8cm, 50 pc/PAK
TLC-Plates ALUGRAM NANO SIL NH2/UV 4x8cm, 50 pc/PAK
Item number: MN818182
Brand: Macherey-Nagel
€206.00
Product Image of TLC-Plates ALUGRAM RP-2/UV254, 20x20cm, 25 pc/PAK
TLC-Plates ALUGRAM RP-2/UV254, 20x20cm, 25 pc/PAK
Item number: MN818171
Brand: Macherey-Nagel
€272.00
Product Image of TLC-Plates ALUGRAM SIL G, 10x20cm, 20 pc/PAK
TLC-Plates ALUGRAM SIL G, 10x20cm, 20 pc/PAK
Item number: MN818163
Brand: Macherey-Nagel
€68.20
Product Image of TLC-Plates ALUGRAM SIL G/UV 254, 10x20cm, 20 pc/PAK
TLC-Plates ALUGRAM SIL G/UV 254, 10x20cm, 20 pc/PAK
Item number: MN818162
Brand: Macherey-Nagel
€68.20

Selection of the Solvent
The solvent is selected according to elution strength. With the help of a quick test you can test different solvents and find the suitable one. 

Sample Application
It is common to use a glass capillary as a dot or short line. Too wide substance zones during application lead to poor separation, as the zones become even wider during separation. After application, the solvent is allowed to evaporate, which can be accelerated by using a dryer.

Development
A common method is to use a development chamber. The eluent is poured into the bottom of the chamber.  The saturation of the chamber with the solvent vapour is necessary for a reproducible running distance. The TLC plate with the sample is then positioned in the chamber. The separation is complete when the eluent has risen to the upper end of the TLC plate. Now the TLC plate can be removed and dried accordingly.

Evaluation
The evaluation depends on the aim of the chromatographic analysis. For qualitative determinations it is easiest to run comparison substances. Quantitative evaluations are possible via corresponding calibration measurements. The area of the substance spots is used or a photometric evaluation is carried out on the layer. However, the latter requires more equipment.