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DURAN® borosilicate glass 3.3 is resistant to water, neutral and acid solutions, concentrated acids and acid mixtures, chlorine, bromine, iodine and organic substances. Further, borosilicate glass 3.3 is highly temperature resistant and ideally suitable for manufacturing reaction vessels. However at the maximum usage temperature of 250 °C and the maximum operating pressure, the temperature difference in the glass wall of the flat flange reaction vessels must not exceed 30 °C.