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Precolumns (guard columns) and precolumn Cartridges for HPLC

Separating columns with modern solid phases are critical components of HPLC analysis. It is important to protect these valuable ingredients from contamination to ensure optimal and consistent separation. In order to prolong the "life" of your HPLC columns, it is advisable to use precolumns. Precolumns offer the advantage in HPLC that they also retain molecules which would form an irreversible bond with the column material. The precolumns should be exchanged regularly. A good indication of the time of the exchange is a gradual increase in the back pressure: For more information, see the care and maintenance of HPLC columns. We carry a wide range of solid phase and stainless steel cartridges for HPLC and UHPLC from the best manufacturers.

 

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Guard Columns

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  1. Chiral Technologies GUARD CARTRIDGE HOLDER
    Chiral

    Chiral Technologies GUARD CARTRIDGE HOLDER

    $160.00
    sku: DAIC00011
  2. Column Protection System Guard Column Holder
    Macherey-Nagel

    Column Protection System Guard Column Holder

    $166.00
    sku: MN718966
  3. Universal Reversed Phase (RP) PreColumn Cartridge 10x4mm for Columns with 3, 4 and 4,6mm ID, 5/PAK
    Altmann Analytik

    Universal Reversed Phase (RP) PreColumn Cartridge 10x4mm for Columns with 3, 4 and 4,6mm ID, 5/PAK

    $170.40
    sku: AAVRP-501040-5
  4. Cartridge Holder for 4 mm Cartridges 2 pc/PAK
    Agilent Technologies

    Cartridge Holder for 4 mm Cartridges 2 pc/PAK

    $458.00
    sku: AG5021-1845
  5. GUARD CARTRIDGE HOLDER FOR HPLC COLUMNS
    Chiral

    GUARD CARTRIDGE HOLDER FOR HPLC COLUMNS

    $180.00
    sku: DAIC00081
  6. VP Guard column holder 8 mm
    Macherey-Nagel

    VP Guard column holder 8 mm

    $255.00
    sku: MN718251
  7. VP Guard column holder 32 mm (short)
    Macherey-Nagel

    VP Guard column holder 32 mm (short)

    $496.00
    sku: MN718253
  8. manu-CART cartridge holder for LiChroCART 25-4 HPLC cartridges
    Merck

    manu-CART cartridge holder for LiChroCART 25-4 HPLC cartridges

    $415.00
    sku: MC1500170001
  9. manu-CART NT cartridge holder for LiChroCART 2,3,4,4.6 mm i.d. HPLC cartridges
    Merck

    manu-CART NT cartridge holder for LiChroCART 2,3,4,4.6 mm i.d. HPLC cartridges

    $525.00
    sku: MC1514860001
  10. HPLC Guard Cartridge XTerra Shield RP18 125Å 5 µm 10 mm X 10 mm, L1 2 - 12pH Range, Low Silan. Act., 175 m2/g, EndCapped, Spher., 15% Carb. Load
    Waters

    HPLC Guard Cartridge XTerra Shield RP18 125Å 5 µm 10 mm X 10 mm

    $260.00
    sku: WT186001006
  11. HPLC Guard Cartridge XTerra MS C18 125Å 10 µm 19 mm X 10 mm, 1 - 12pH Range, Low Silan. Act., 175 m2/g, EndCapped, Spher., 15.5% Carb. Load
    Waters

    HPLC Guard Cartridge XTerra MS C18 125Å 10 µm 19 mm X 10 mm

    $443.00
    sku: WT186001034
  12. HPLC Guard Cartridge XTerra MS C18 125Å 5 µm 19 mm X 10 mm, 1 - 12pH Range, Low Silan. Act., 175 m2/g, EndCapped, Spher., 15.5% Carb. Load
    Waters

    HPLC Guard Cartridge XTerra MS C18 125Å 5 µm 19 mm X 10 mm

    $443.00
    sku: WT186001104
  13. HPLC Guard Cartridge XTerra Shield RP18 125Å 10 µm 7.8 mm X 10 mm, L1 2 - 12pH Range, Low Silan. Act., 175 m2/g, EndCapped, Spher., 15% Carb. Load
    Waters

    HPLC Guard Cartridge XTerra Shield RP18 125Å 10 µm 7.8 mm X 10 mm

    $255.00
    sku: WT186001174
  14. HPLC Guard Column Envirogel GPC Cleanup, 15 µm, 4.6x30 mm, 100 - 10K, Cyclohexane/Ethyl Acetate, 2 - 12 Ph Range, Spherical
    Waters

    HPLC Guard Column Envirogel GPC Cleanup, 15 µm, 4.6x30 mm

    $481.00
    sku: WT186001914
  15. HPLC Guard Cartridge XTerra MS C18 125Å 5 µm 4.6 mm X 10 mm 3/PK, L1 1 - 12pH Range, Low Silan. Act., 175 m2/g, EndCapped, Spher., 15.5% Carb. Load
    Waters

    HPLC Guard Cartridge XTerra MS C18 125Å 5 µm 4.6 mm X 10 mm 3/PK

    $356.00
    sku: WT186001920
  16. HPLC Guard Cartridge SunFire C18 100Å 10 µm 10 mm X 10 mm, 2 - 8pH Range, Low Silan. Act., 340 m2/g, EndCapped, Spher., 16 % Carbon Load
    Waters

    HPLC Guard Cartridge SunFire C18 100Å 10 µm 10 mm X 10 mm

    $260.00
    sku: WT186002663
  17. HPLC Guard Cartridge SunFire C18 100Å 10 µm 19 mm X 10 mm, 2 - 8pH Range, Low Silan. Act., 340 m2/g, EndCapped, Spher., 16 % Carbon Load
    Waters

    HPLC Guard Cartridge SunFire C18 100Å 10 µm 19 mm X 10 mm

    $443.00
    sku: WT186002666
  18. HPLC Guard Column MassPREP Phenyl, 10 mm 2.1 mm 20 µm 1000 Å 2/PAK, 2 - 12pH Range, Low Silan. Act., EndCapped, Spher.
    Waters

    HPLC Guard Column MassPREP Phenyl, 10 mm 2.1 mm 20 µm 1000 Å 2/PAK

    $344.00
    sku: WT186002785
  19. HPLC Guard Cartridge XBridge BEH Shield RP18 130Å 3.5 µm 3 mm X 20 mm 2/PK, L1 2 - 11pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 17% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH Shield RP18 130Å 3.5 µm 3 mm X 20 mm 2/PK

    $356.00
    sku: WT186003069
  20. HPLC Guard Cartridge XBridge BEH Shield RP18 130Å 3.5 µm 4.6 mm X 20 mm 2/PK, Hybrid, L1 2 - 11pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 17% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH Shield RP18 130Å 3.5 µm 4.6 mm X 20 mm 2/PK

    $356.00
    sku: WT186003070
  21. HPLC Guard Cartridge XBridge BEH Phenyl 130Å 5 µm 10 mm X 10 mm, L11, 1 - 12pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 15% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH Phenyl 130Å 5 µm 10 mm X 10 mm

    $292.00
    sku: WT186003354
  22. HPLC Guard Cartridge XBridge BEH C18 135Å 10 µm 10 mm X 10 mm, L1, 1 - 12pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 18% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH C18 135Å 10 µm 10 mm X 10 mm

    $292.00
    sku: WT186003889
  23. HPLC Guard Cartridge XBridge BEH C18 130Å 10 µm 19 mm X 10 mm, L1, 1 - 12pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 18% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH C18 130Å 10 µm 19 mm X 10 mm

    $443.00
    sku: WT186003892
  24. HPLC Guard Cartridge XBridge BEH Shield RP18 130Å 10 µm 19 mm X 10 mm, L1, 1 - 12pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 13% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH Shield RP18 130Å 10 µm 19 mm X 10 mm

    $443.00
    sku: WT186003991
  25. HPLC Guard Cartridge XSelect CSH Fluoro Phenyl 130Å 5 µm 19 mm X 10 mm, L43, 1 - 8pH Range, Low Silan. Act., 185 m2/g, Spher., 10% Carb. Load
    Waters

    HPLC Guard Cartridge XSelect CSH Fluoro Phenyl 130Å 5 µm 19 mm X 10 mm

    $443.00
    sku: WT186005431
  26. SFC Guard Column ACQUITY UPC2 Viridis HSS C18 SB VanGuard, 100Å, 1.8 µm, 2.1x5 mm, 3/pkg, High Silan. Act.230 m2/g, Spher., 8.5% Carb. Load
    Waters

    SFC Guard Column ACQUITY UPC2 Viridis HSS C18 SB VanGuard, 100Å, 1.8 µm, 2.1x5 mm, 3/pkg

    $741.00
    sku: WT186006616
  27. UPLC Guard Column ACQUITY Peptide CSH C18 VanGuard, 130A, 5x2.1mm, 1.7µm, 3/PAK, Hybrid, L1, 1 - 11pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 15% Carb. Load
    Waters

    UPLC Guard Column ACQUITY Peptide CSH C18 VanGuard, 130A, 5x2.1mm, 1.7µm , 3/PAK

    $802.00
    sku: WT186006939
  28. HPLC Guard Column PREP NOVA-PAK HR C18 10 mm 40 mm 6 µm 60 Å, 2/PAK, 2 - 8pH Range, Med. Silan. Act., 120 m2/g, EndCapped, Spher., 7.3 % Carbon Load
    Waters

    HPLC Guard Column PREP NOVA-PAK HR C18 10 mm 40 mm 6 µm 60 Å, 2/PAK

    $925.00
    sku: WTWAT037854
  29. Sentry Guard Holder Integrated
    Waters

    Sentry Guard Holder Integrated

    $162.00
    sku: WTWAT046905
  30. Sentry Guard Holder Universal
    Waters

    Sentry Guard Holder Universal

    $196.00
    sku: WTWAT046910
  31. HPLC Guard Column SYMMETRY C8 3.5U 2.1X30, 2 - 8pH Range, Low Silan. Act., 335 m2/g, EndCapped, Spher., 11.7% Carb. Load
    Waters

    HPLC Guard Column SYMMETRY C8 3.5U 2.1X30

    $606.00
    sku: WTWAT058977
  32. Guard-Pak Holder
    Waters

    Guard-Pak Holder

    $499.00
    sku: WTWAT088141
  33. Sentry 2.1mm Guard Holder Pkg
    Waters

    Sentry 2.1mm Guard Holder Pkg

    $265.00
    sku: WTWAT097958
  34. HPLC Guard Cartridge Symmetry C18 100Å 3.5 µm 2.1 mm X 10 mm 2/PK, L1 2 - 8pH Range, Low Silan. Act., 335 m2/g, EndCapped, Spher., 19.1% Carb. Load
    Waters

    HPLC Guard Cartridge Symmetry C18 100Å 3.5 µm 2.1 mm X 10 mm 2/PK

    $356.00
    sku: WTWAT106127
  35. HPLC Guard Cartridge Symmetry C8 100Å 3.5 µm 2.1 mm X 10 mm 2/PK, Class:L7 2 - 8pH Range, Low Silan. Act., 335 m2/g, EndCapped, Spher., 11.7% Carb. Load
    Waters

    HPLC Guard Cartridge Symmetry C8 100Å 3.5 µm 2.1 mm X 10 mm 2/PK

    $356.00
    sku: WTWAT106128
  36. HPLC Guard Cartridge Symmetry Shield RP 8 100Å 3.5 µm 2.1 mm X 10 mm 2/PK, L7 2 - 8pH Range, Low Silan. Act., 335 m2/g, EndCapped, Spher., 15% Carb. Load
    Waters

    HPLC Guard Cartridge Symmetry Shield RP 8 100Å 3.5 µm 2.1 mm X 10 mm 2/PK

    $356.00
    sku: WTWAT106129
  37. External Guard Cartridge Holder to screw on Head f
    YMC

    External Guard Cartridge Holder to screw on Head f

    $251.90
    sku: YMXPGCH-Q1
  38. HPLC Guard Column Asahipak NH2P-50G 4A, 5 µm, 4.6 x 10 mm
    Shodex

    HPLC Guard Column Asahipak NH2P-50G 4A, 5 µm, 4.6 x 10 mm

    $451.00
    sku: SDF6710016
  39. HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak

    $390.00
    sku: DAIC87511
  40. Acclaim SST Guard Cartridge Holder V-2
    Thermo Fisher Scientific

    Acclaim SST Guard Cartridge Holder V-2

    $213.60
    sku: TF069580
  41. Acclaim Guard Kit (Holder and coupler) V-2
    Thermo Fisher Scientific

    Acclaim Guard Kit (Holder and coupler) V-2

    $228.00
    sku: TF069707
  42. UNIGUARD Drop-in Holder, 3.0/2.1mm
    Thermo Fisher Scientific

    UNIGUARD Drop-in Holder, 3.0/2.1mm

    $187.68
    sku: TF852-00
  43. Reliance Guard Cartridge Holder
    Agilent Technologies

    Reliance Guard Cartridge Holder

    $72.60
    sku: AG820565-001
  44. VP Guard column holder 16 mm (short
    Macherey-Nagel

    VP Guard column holder 16 mm (short

    $305.00
    sku: MN718256
  45. Replacement connector for guard column holder, 5/PAK
    Macherey-Nagel

    Replacement connector for guard column holder, 5/PAK

    $28.50
    sku: MN718968
  46. HPLC Guard Column DELTA-PAK C4 G-P Einsatz C4 10 mm 40 mm 15 µm 300 Å
    Waters

    HPLC Guard Column DELTA-PAK C4 G-P Einsatz C4 10 mm 40 mm 15 µm 300 Å

    $715.00
    sku: WTWAT037851
  47. In Line Guard Cart Holder Kit for 4.6x10mm Guards
    Waters

    In Line Guard Cart Holder Kit for 4.6x10mm Guards

    $150.00
    sku: WTPSS830008
  48. All-Guard Cartridge Holder, old no: 3112782/N
    Grace

    All-Guard Cartridge Holder, old no: 3112782/N

    $144.00
    sku: GR80101
  49. HPLC Guard Column Holder indirect, 10 x 3 mm
    Altmann Analytik

    HPLC Guard Column Holder indirect, 10 x 3 mm

    $158.40
    sku: AAHI-01030
  50. HPLC Guard Column Holder indirect, 10 x 4 mm
    Altmann Analytik

    HPLC Guard Column Holder indirect, 10 x 4 mm

    $158.40
    sku: AAHI-01040
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Consistent Resolution in RP Chromatography

It makes sense to ensure consistent resolution in reverse-phase (RP) chromatography by removing non-polar contaminants, particularly in diagnostics applications and food analysis. With our large selection of stainless steel guard columns and stationary phases, we can meet your needs for HPLC hardware and consumables.

Whenever consistent resolution and reproducibility are required, e.g. in samples from biological matrices, our customers can select from a wide variety of bonded solid phases. From food analysis to forensic toxicology, the routine for every chromatographic method is to use column guards to protect your investment and to ensure consistent operations at only a fraction of the cost for a new HPLC or UHPLC column.

When using HPLC guard columns to protect the columns, a column holder is required. The following diagrams show you the connection possibilities when you need a precolumn to an HPLC column (column connectors have to be ordered separately):

Wide Range of Manufacturers:

We offer all trusted brands, such as Agilent Technologies, Chiral, Grace, Macherey Nagel and Sielc. As a cost-effective alternative, we carry a large selection of our own high quality brand Altmann Analytik.

 

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  54. (6)
  55. (5)
  56. (4)
  57. (2)
  58. (5)
  59. (37)
  60. (4)
  61. (2)
  62. (2)
  63. (8)
  64. (22)
  65. (10)
  66. (223)
  67. (3)
  68. (4)
  69. (8)
  70. (27)
  71. (11)
  72. (7)
  73. (4)
  74. (186)
  75. (6)
  76. (8)
  77. (4)
  78. (1)
  79. (3)
  80. (4)
  81. (10)
  82. (2)
  83. (3)
  84. (34)
  85. (75)
  86. (1)
  87. (72)
  88. (1)
  89. (2)
  90. (4)
  91. (6)
  92. (6)
  93. (1)
  94. (1)
  95. (3)
  96. (2)
  97. (2)
  98. (58)
  99. (10)
  100. (13)
  101. (109)
  102. (981)
  103. (2)
  104. (76)
  105. (2)
  106. (1)
  107. (5)
  108. (2)
  109. (2)
  110. (6)
category
  1. (212)
  2. (3)
  3. (53)
  4. (9345)
modus
  1. (2)
  2. (223)
  3. (264)
  4. (503)
  5. (9)
  6. (730)
  7. (1)
  8. (2241)
  9. (442)
  10. (5579)
  11. (167)
  12. (68)
  13. (2)
type
  1. (1)
  2. (17)
  3. (1)
  4. (15)
  5. (1)
  6. (1)
  7. (55)
  8. (1)
  9. (106)
  10. (1)
  11. (1)
  12. (1)
length
  1. (3)
  2. (22)
  3. (176)
  4. (1738)
  5. (90)
  6. (26)
  7. (3859)
  8. (49)
  9. (1)
  10. (1)
  11. (83)
  12. (1)
  13. (1685)
  14. (1)
  15. (1)
  16. (14)
  17. (74)
  18. (29)
  19. (17)
  20. (15)
  21. (2)
  22. (2)
  23. (254)
  24. (16)
  25. (1)
  26. (19)
  27. (1)
  28. (1)
  29. (3)
  30. (2)
  31. (9)
  32. (1)
  33. (1)
  34. (1)
inner diameter
  1. (1)
  2. (1)
  3. (1)
  4. (2)
  5. (44)
  6. (43)
  7. (6)
  8. (1)
  9. (1)
  10. (1)
  11. (1)
  12. (3)
  13. (182)
  14. (12)
  15. (1721)
  16. (1073)
  17. (687)
  18. (307)
  19. (127)
  20. (2025)
  21. (1411)
  22. (3)
  23. (28)
  24. (3)
  25. (5)
  26. (36)
  27. (9)
  28. (41)
  29. (39)
  30. (1)
  31. (5)
  32. (404)
  33. (1)
  34. (14)
  35. (49)
  36. (115)
  37. (73)
  38. (17)
  39. (5)
  40. (17)
  41. (12)
  42. (86)
  43. (9)
  44. (6)
  45. (10)
  46. (1)
particle size
  1. (7)
  2. (32)
  3. (3)
  4. (138)
  5. (1)
  6. (37)
  7. (40)
  8. (36)
  9. (2)
  10. (147)
  11. (45)
  12. (138)
  13. (1337)
  14. (1)
  15. (124)
  16. (250)
  17. (3865)
  18. (27)
  19. (291)
  20. (1)
  21. (53)
  22. (4)
  23. (13)
  24. (1134)
  25. (14)
  26. (50)
  27. (19)
  28. (1)
  29. (7)
  30. (5)
  31. (2)
  32. (1)
  33. (2)
  34. (11)
  35. (1)
  36. (2)
  37. (3)
pore size
  1. (1)
  2. (2)
  3. (90)
  4. (14)
  5. (62)
  6. (178)
  7. (53)
  8. (59)
  9. (12)
  10. (2285)
  11. (38)
  12. (908)
  13. (92)
  14. (205)
  15. (12)
  16. (111)
  17. (9)
  18. (46)
  19. (221)
  20. (4)
  21. (541)
  22. (4)
  23. (8)
  24. (59)
  25. (4)
  26. (59)
  27. (2)
  28. (2)
  29. (27)
pH range
  1. (1)
  2. (5)
  3. (84)
  4. (64)
  5. (188)
  6. (60)
  7. (49)
  8. (20)
  9. (8)
  10. (7)
  11. (24)
  12. (2)
  13. (2)
  14. (3)
  15. (2)
  16. (25)
  17. (63)
  18. (5)
  19. (1)
  20. (4)
  21. (4)
  22. (51)
  23. (733)
  24. (1144)
  25. (124)
  26. (38)
  27. (1)
  28. (19)
  29. (343)
  30. (30)
  31. (19)
  32. (2)
  33. (38)
  34. (19)
  35. (26)
  36. (8)
  37. (6)
  38. (16)
  39. (2)
  40. (3)
  41. (2)
  42. (33)
  43. (6)
  44. (2)
  45. (16)
  46. (2)
  47. (2)
  48. (1)
  49. (1)
  50. (1)
USP number
  1. (1929)
  2. (2)
  3. (341)
  4. (1)
  5. (714)
  6. (179)
  7. (7)
  8. (278)
  9. (217)
  10. (23)
  11. (19)
  12. (2)
  13. (2)
  14. (2)
  15. (122)
  16. (37)
  17. (14)
  18. (4)
  19. (7)
  20. (7)
  21. (275)
  22. (18)
  23. (17)
  24. (3)
  25. (28)
  26. (1)
  27. (18)
  28. (19)
  29. (2)
  30. (1)
  31. (20)
  32. (9)
  33. (5)
  34. (1)
  35. (3)
  36. (3)
  37. (7)
  38. (4)
  39. (2)
endcapping
  1. (89)
  2. (628)
  3. (2227)
  4. (13)
  5. (1)
column application
  1. (13)
  2. (18)
  3. (13)
  4. (15)
  5. (14)
  6. (13)
  7. (26)
  8. (21)
  9. (30)
  10. (14)
  11. (32)
  12. (7)
  13. (14)
  14. (7)
  15. (1)
  16. (1)
  17. (12)
  18. (8)
  19. (6)
  20. (19)
  21. (6)
  22. (13)
  23. (12)
  24. (7)
  25. (8)
  26. (20)
  27. (20)
  28. (13)
  29. (41)
  30. (13)
  31. (13)
  32. (26)
  33. (15)
  34. (12)
  35. (7)
  36. (12)
carbon load
  1. (29)
  2. (24)
  3. (1)
  4. (126)
  5. (10)
  6. (2)
  7. (3)
  8. (2)
  9. (1)
  10. (12)
  11. (3)
  12. (6)
  13. (31)