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Precolumns (guard columns) and precolumn cartridges for HPLC

Separation columns with modern solid phases are critical components of the HPLC system. Careful handling and protection against impurities is necessary to ensure optimum and consistent separation results. In order to extend the life of your HPLC columns, it is advisable to use guard columns. They are able to remove molecules which would form an irreversible bond with the material of the analytical column. Guard coloumns need to be changed on a regular basis. A good indication on when to change a precolumn is a gradual increase in the back pressure. For more information on the storage and maintenance of HPLC column, click here.

We carry a wide range of solid phase and stainless steel cartridges for HPLC and UHPLC.

Click here for more Information on guard columns.

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Guard Columns

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  1. Chiral Technologies GUARD CARTRIDGE HOLDER
    Chiral

    Chiral Technologies GUARD CARTRIDGE HOLDER

    $200.00
    sku: DAIC00011
  2. Column Protection System Guard Column Holder
    Macherey-Nagel

    Column Protection System Guard Column Holder

    $182.20
    sku: MN718966
  3. Universal Reversed Phase (RP) Guard Column Cartridge 10x4mm for Columns with 3, 4 and 4.6mm ID, 5/PAK
    Altmann Analytik

    Universal Reversed Phase (RP) Guard Column Cartridge 10x4mm for Columns with 3, 4 and 4.6mm ID, 5/PAK

    $144.00
    sku: AAVRP-501040-5
  4. GUARD CARTRIDGE HOLDER FOR HPLC COLUMNS
    Chiral

    GUARD CARTRIDGE HOLDER FOR HPLC COLUMNS

    $223.53
    sku: DAIC00081
  5. manu-CART NT cartridge holder for LiChroCART 2,3,4,4.6 mm i.d. HPLC cartridges
    Merck

    manu-CART NT cartridge holder for LiChroCART 2,3,4,4.6 mm i.d. HPLC cartridges

    $550.00
    sku: MC1514860001
  6. HPLC Guards Accucore 150-C4 10x2.1mm, 4/PAK
    Thermo Fisher Scientific

    HPLC Guards Accucore Defender 150-C4 10x2.1mm, 2.6µm, 4/PAK

    $607.32
    sku: TF16526-012105
  7. HPLC guard cartridge 10x4mm 2.4um BDS C18
    Thermo Fisher Scientific

    HPLC guard cartridge 10x4mm 2.4um BDS C18

    $511.56
    sku: TF28102-014001
  8. HPLC Guard Cartridge XTerra MS C18 125Å 5 µm 4.6 mm X 10 mm 3/PK, L1 1 - 12pH Range, Low Silan. Act., 175 m2/g, EndCapped, Spher., 15.5% Carb. Load
    Waters

    HPLC Guard Cartridge XTerra MS C18 125Å 5 µm 4.6 mm X 10 mm 3/PK

    $372.00
    sku: WT186001920
  9. HPLC Guard Cartridge SunFire C18 100Å 10 µm 19 mm X 10 mm, 2 - 8pH Range, Low Silan. Act., 340 m2/g, EndCapped, Spher., 16 % Carbon Load
    Waters

    HPLC Guard Cartridge SunFire C18 100Å 10 µm 19 mm X 10 mm

    $465.00
    sku: WT186002666
  10. HPLC Guard Column MassPREP Phenyl, 10 mm 2.1 mm 20 µm 1000 Å 2/PAK, 2 - 12pH Range, Low Silan. Act., EndCapped, Spher.
    Waters

    HPLC Guard Column MassPREP Phenyl, 10 mm 2.1 mm 20 µm 1000 Å 2/PAK

    $364.00
    sku: WT186002785
  11. HPLC Guard Cartridge XBridge BEH Shield RP18 130Å 3.5 µm 4.6 mm X 20 mm 2/PK, Hybrid, L1 2 - 11pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 17% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH Shield RP18 130Å 3.5 µm 4.6 mm X 20 mm 2/PK

    $372.00
    sku: WT186003070
  12. HPLC Guard Cartridge XBridge BEH Phenyl 130Å 5 µm 10 mm X 10 mm, L11, 1 - 12pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 15% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH Phenyl 130Å 5 µm 10 mm X 10 mm

    $307.00
    sku: WT186003354
  13. HPLC Guard Cartridge XBridge BEH C18 130Å 10 µm 19 mm X 10 mm, L1, 1 - 12pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 18% Carb. Load
    Waters

    HPLC Guard Cartridge XBridge BEH C18 130Å 10 µm 19 mm X 10 mm

    $465.00
    sku: WT186003892
  14. UPLC Guard Column ACQUITY Peptide CSH C18 VanGuard, 130A, 5x2.1mm, 1.7µm, 3/PAK, Hybrid, L1, 1 - 11pH Range, Low Silan. Act., 185 m2/g, EndCapped, Spher., 15% Carb. Load
    Waters

    UPLC Guard Column ACQUITY Peptide CSH C18 VanGuard, 130A, 5x2.1mm, 1.7µm , 3/PAK

    $849.00
    sku: WT186006939
  15. Sentry Guard Holder Integrated
    Waters

    Sentry Guard Holder Integrated

    $169.00
    sku: WTWAT046905
  16. Sentry Guard Holder Universal
    Waters

    Sentry Guard Holder Universal

    $205.00
    sku: WTWAT046910
  17. Guard-Pak Holder
    Waters

    Guard-Pak Holder

    $521.00
    sku: WTWAT088141
  18. Sentry 2.1mm Guard Holder Pkg
    Waters

    Sentry 2.1mm Guard Holder Pkg

    $277.00
    sku: WTWAT097958
  19. HPLC Guard Cartridge Symmetry C18 100Å 3.5 µm 2.1 mm X 10 mm 2/PK, L1 2 - 8pH Range, Low Silan. Act., 335 m2/g, EndCapped, Spher., 19.1% Carb. Load
    Waters

    HPLC Guard Cartridge Symmetry C18 100Å 3.5 µm 2.1 mm X 10 mm 2/PK

    $372.00
    sku: WTWAT106127
  20. HPLC Guard Cartridge Symmetry C8 100Å 3.5 µm 2.1 mm X 10 mm 2/PK, Class:L7 2 - 8pH Range, Low Silan. Act., 335 m2/g, EndCapped, Spher., 11.7% Carb. Load
    Waters

    HPLC Guard Cartridge Symmetry C8 100Å 3.5 µm 2.1 mm X 10 mm 2/PK

    $372.00
    sku: WTWAT106128
  21. HPLC Guard Column SUGAR SP-G 6B, Pb2+, 10 µm, 6 x 50 mm
    Shodex

    HPLC Guard Column SUGAR SP-G 6B, Pb2+, 10 µm, 6 x 50 mm

    $472.00
    sku: SDF6700081
  22. HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak

    $410.00
    sku: DAIC87511
  23. Acclaim SST Guard Cartridge Holder V-2
    Thermo Fisher Scientific

    Acclaim SST Guard Cartridge Holder V-2

    $235.62
    sku: TF069580
  24. Acclaim Guard Kit (Holder and coupler) V-2
    Thermo Fisher Scientific

    Acclaim Guard Kit (Holder and coupler) V-2

    $252.00
    sku: TF069707
  25. UNIGUARD Drop-in Holder, 3.0/2.1mm
    Thermo Fisher Scientific

    UNIGUARD Drop-in Holder, 3.0/2.1mm

    $211.34
    sku: TF852-00
  26. In Line Guard Cart Holder Kit for 4.6x10mm Guards
    Waters

    In Line Guard Cart Holder Kit for 4.6x10mm Guards

    $157.00
    sku: WTPSS830008
  27. All-Guard Cartridge Holder, old no: 3112782/N
    Grace

    All-Guard Cartridge Holder, old no: 3112782/N

    $144.00
    sku: GR80101
  28. HPLC Guard Column Holder indirect, 10 x 3 mm
    Altmann Analytik

    HPLC Guard Column Holder indirect, 10 x 3 mm

    $158.40
    sku: AAHI-01030
  29. HPLC Guard Column Holder indirect, 10 x 4 mm
    Altmann Analytik

    HPLC Guard Column Holder indirect, 10 x 4 mm

    $158.40
    sku: AAHI-01040
  30. Cartridge Column Holder 2.1x20mm
    Waters

    Cartridge Column Holder 2.1x20mm

    $304.00
    sku: WT186000262
  31. HPLC VanGuard Cartridge Holder
    Waters

    HPLC VanGuard Cartridge Holder

    $174.00
    sku: WT186007949
  32. HPLC Guard column Poroshell SB 300 C18, 5 µm, 1 x 17 mm, 3 Stk/Pkg
    Agilent Technologies

    HPLC Guard column Poroshell SB 300 C18, 5 µm, 1 x 17 mm, 3 pc/pak

    $560.00
    sku: AG5185-5968
  33. HPLC Guard Column Bio SEC-3, 300Å, 3 µm, 7,8 x 50 mm
    Agilent Technologies

    HPLC Guard Column Bio SEC-3, 300Å, 3 µm, 7,8 x 50 mm

    $969.00
    sku: AG5190-2515
  34. HPLC Guard Column Bio SEC-5, 500Å, 5 µm, 7,8 x 50 mm
    Agilent Technologies

    HPLC Guard Column Bio SEC-5, 500Å, 5 µm, 7,8 x 50 mm

    $720.00
    sku: AG5190-2535
  35. UHPLC Guard Column Poroshell 120 EC-C18, 2,7 µm, 3 x 5 mm, 3 pc/pak
    Agilent Technologies

    UHPLC Guard Column Poroshell 120 EC-C18, 2,7 µm, 3 x 5 mm, 3 pc/pak

    $629.00
    sku: AG823750-911
  36. HPLC MetaGuard column Polaris C18-A, 180Å, 3 µm, 2,0 mm, 3 pc/pak
    Agilent Technologies

    HPLC MetaGuard column Polaris C18-A, 180Å, 3 µm, 2,0 mm, 3 pc/pak

    $371.00
    sku: AGA2001MG2
  37. HPLC Guard cartridge (ChromSep) Pursuit PAH, 200Å, 3 x 10 mm, 3 pc/pak
    Agilent Technologies

    HPLC Guard cartridge (ChromSep) Pursuit PAH, 200Å, 3 x 10 mm, 3 pc/pak

    $372.00
    sku: AGA7001CG3
  38. HPLC Guard Cartridge CHIRALCEL OB-H, 10 x 4 mm, 5 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL OB-H, 10 x 4 mm, 5 µm, 3 pc/pak

    $340.00
    sku: DAIC12311
  39. HPLC Guard Cartridge CHIRALCEL® OD-H, 10 x 4 mm, 5 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL® OD-H, 10 x 4 mm, 5 µm, 3 pc/pak

    $260.00
    sku: DAIC14311
  40. HPLC Guard Cartridge CHIRALCEL® OD-3, 10 x 4 mm, 3 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL® OD-3, 10 x 4 mm, 3 µm, 3 pc/pak

    $310.00
    sku: DAIC14511
  41. HPLC Guard Cartridge CHIRALCEL OD-R, 10 x 4 mm, 10 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL OD-R, 10 x 4 mm, 10 µm, 3 pc/pak

    $260.00
    sku: DAIC14611
  42. HPLC Guard Cartridge CHIRALCEL® OD-RH, 10 x 4 mm, 5 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL® OD-RH, 10 x 4 mm, 5 µm, 3 pc/pak

    $260.00
    sku: DAIC14711
  43. HPLC Guard Cartridge CHIRALCEL® OD-3R, 10 x 4 mm, 3 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL® OD-3R, 10 x 4 mm, 3 µm, 3 pc/pak

    $310.00
    sku: DAIC14811
  44. HPLC Guard Cartridge CHIRALCEL® OJ-H, 10 x 4 mm, 5 µm, 3 pc/PAK
    Chiral

    HPLC Guard Cartridge CHIRALCEL® OJ-H, 10 x 4 mm, 5 µm, 3 pc/PAK

    $340.00
    sku: DAIC17311
  45. HPLC Guard Cartridge CHIRALCEL® OJ-3, 10 x 4 mm, 3 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL® OJ-3, 10 x 4 mm, 3 µm, 3 pc/pak

    $400.00
    sku: DAIC17511
  46. HPLC Guard Cartridge CHIRALCEL® OJ-RH, 10 x 4 mm, 5 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL® OJ-RH, 10 x 4 mm, 5 µm, 3 pc/pak

    $340.00
    sku: DAIC17711
  47. HPLC Guard Cartridge CHIRALCEL® OJ-3R, 10 x 4 mm, 3 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALCEL® OJ-3R, 10 x 4 mm, 3 µm, 3 pc/pak

    $400.00
    sku: DAIC17811
  48. HPLC Guard Cartridge CHIRALPAK® AD-H, 10 x 4 mm, 5 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALPAK® AD-H, 10 x 4 mm, 5 µm, 3 pc/pak

    $260.00
    sku: DAIC19311
  49. HPLC Guard Cartridge CHIRALPAK® AD-3, 10 x 4 mm, 3 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALPAK® AD-3, 10 x 4 mm, 3 µm, 3 pc/pak

    $310.00
    sku: DAIC19511
  50. HPLC Guard Cartridge CHIRALPAK® AD-RH, 10 x 4 mm, 5 µm, 3 pc/pak
    Chiral

    HPLC Guard Cartridge CHIRALPAK® AD-RH, 10 x 4 mm, 5 µm, 3 pc/pak

    $260.00
    sku: DAIC19711
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Connecting HPLC column with precolumn holder (direct and indirect coupling)

If you want to protect your column from contamination by connecting a precolumn cartridge upstream, you always need a precolumn holder as well. At Analytics-Shop you will find HPLC precolumns from all well-known manufacturers, from Agilent Technologies and Chiral to Macherey-Nagel, Merck, Thermo Scientific, Waters and Whatman. High quality and at the same time very affordable alternatives of precolumns and columns are products of our house brand Altmann Analytik.

Indirect pre-column holders are compatible with the common columns of all manufacturers. For this you need an additional column connector as an intermediate piece between column and pre-column holder. The following graphic shows the connection possibilities if you need a pre-column for an HPLC column (column connectors must be ordered separately):

 

Selecting precolumns of the appropriate length for HPLC columns

In general, the length of the precolumn should not exceed 10 percent of the column. We therefore recommend

- for columns with length up to 50 mm: precolumns with length 5 mm
- for columns with length from 60 mm to 199 mm: precolumns with length 10 mm
- for columns with length of 200 mm and larger: precolumns with length 20 mm

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  98. (4)
  99. (2)
  100. (5)
  101. (2)
  102. (2)
  103. (7)
  104. (6)
category
  1. (168)
  2. (3)
  3. (6)
  4. (8289)
  5. (1)
modus
  1. (2066)
  2. (4692)
  3. (244)
  4. (360)
  5. (253)
  6. (663)
  7. (390)
  8. (7)
  9. (9)
  10. (9)
  11. (152)
  12. (2)
Manufacturer of device
  1. (1)
device model
  1. (1)
  2. (1)
type
  1. (1)
  2. (16)
  3. (1)
  4. (7)
  5. (1)
  6. (1)
  7. (43)
  8. (1)
  9. (88)
  10. (1)
  11. (1)
  12. (1)
length
  1. (3)
  2. (1)
  3. (22)
  4. (173)
  5. (1)
  6. (1652)
  7. (50)
  8. (26)
  9. (3001)
  10. (47)
  11. (1)
  12. (1)
  13. (75)
  14. (1)
  15. (1421)
  16. (1)
  17. (2)
  18. (5)
  19. (67)
  20. (27)
  21. (15)
  22. (18)
  23. (2)
  24. (2)
  25. (238)
  26. (17)
  27. (17)
  28. (1)
  29. (8)
  30. (1)
  31. (1)
inner diameter
  1. (16)
  2. (14)
  3. (3)
  4. (1)
  5. (1)
  6. (1)
  7. (1)
  8. (3)
  9. (111)
  10. (12)
  11. (1608)
  12. (863)
  13. (488)
  14. (283)
  15. (129)
  16. (1823)
  17. (1263)
  18. (3)
  19. (30)
  20. (1)
  21. (5)
  22. (31)
  23. (9)
  24. (43)
  25. (49)
  26. (1)
  27. (5)
  28. (271)
  29. (1)
  30. (13)
  31. (49)
  32. (74)
  33. (78)
  34. (5)
  35. (17)
  36. (14)
  37. (207)
  38. (9)
  39. (87)
  40. (1)
particle size
  1. (7)
  2. (38)
  3. (135)
  4. (22)
  5. (37)
  6. (1)
  7. (149)
  8. (46)
  9. (143)
  10. (955)
  11. (1)
  12. (154)
  13. (224)
  14. (49)
  15. (3131)
  16. (20)
  17. (6)
  18. (299)
  19. (1)
  20. (42)
  21. (4)
  22. (13)
  23. (36)
  24. (1094)
  25. (6)
  26. (8)
  27. (48)
  28. (60)
  29. (1)
  30. (4)
  31. (1)
  32. (84)
  33. (1)
  34. (11)
  35. (13)
  36. (1)
  37. (1)
  38. (3)
pore size
  1. (1)
  2. (2)
  3. (133)
  4. (13)
  5. (42)
  6. (143)
  7. (46)
  8. (49)
  9. (16)
  10. (2319)
  11. (25)
  12. (482)
  13. (92)
  14. (213)
  15. (12)
  16. (24)
  17. (72)
  18. (9)
  19. (14)
  20. (46)
  21. (79)
  22. (15)
  23. (466)
  24. (2)
  25. (8)
  26. (50)
  27. (4)
  28. (63)
  29. (2)
  30. (2)
  31. (27)
USP number
  1. (1489)
  2. (2)
  3. (263)
  4. (1)
  5. (520)
  6. (135)
  7. (231)
  8. (163)
  9. (10)
  10. (14)
  11. (2)
  12. (4)
  13. (2)
  14. (70)
  15. (43)
  16. (22)
  17. (5)
  18. (2)
  19. (7)
  20. (187)
  21. (21)
  22. (1)
  23. (3)
  24. (18)
  25. (3)
  26. (17)
  27. (1)
  28. (18)
  29. (18)
  30. (3)
  31. (7)
  32. (5)
  33. (4)
  34. (1)
  35. (5)
  36. (1)
  37. (4)
  38. (7)
  39. (4)
  40. (1)
  41. (4)
  42. (1)
  43. (2)
  44. (6)
pH range
  1. (1)
  2. (6)
  3. (82)
  4. (45)
  5. (141)
  6. (60)
  7. (14)
  8. (15)
  9. (8)
  10. (7)
  11. (3)
  12. (2)
  13. (16)
  14. (1)
  15. (4)
  16. (56)
  17. (621)
  18. (669)
  19. (93)
  20. (43)
  21. (18)
  22. (275)
  23. (31)
  24. (2)
  25. (19)
  26. (18)
  27. (4)
  28. (10)
  29. (2)
  30. (15)
  31. (3)
  32. (4)
  33. (2)
  34. (1)
  35. (6)
  36. (5)
  37. (2)
  38. (1)
  39. (1)
endcapping
  1. (11)
  2. (452)
  3. (1676)
  4. (5)
  5. (1)
column application
  1. (5)
  2. (6)
  3. (4)
  4. (4)
  5. (8)
  6. (3)
  7. (8)
  8. (4)
  9. (4)
  10. (10)
  11. (5)
  12. (2)
  13. (5)
  14. (2)
  15. (4)
  16. (2)
  17. (4)
  18. (2)
  19. (2)
  20. (3)
  21. (7)
  22. (4)
  23. (6)
  24. (9)
  25. (7)
  26. (2)
  27. (2)
  28. (3)
carbon load
  1. (5)
  2. (18)
  3. (112)
  4. (10)
  5. (1)
  6. (1)
  7. (1)
  8. (1)
  9. (2)
  10. (1)
  11. (2)
  12. (1)
  13. (3)
  14. (3)
  15. (6)
  16. (6)
  17. (2)
  18. (59)
  19. (2)
  20. (66)
  21. (31)
  22. (2)
  23. (2)
  24. (2)
  25. (2)
  26. (4)
  27. (1)
  28. (42)
  29. (4)
  30. (5)
  31. (2)
  32. (2)
  33. (1)
  34. (4)
  35. (40)
  36. (4)
  37. (109)
  38. (4)
  39. (9)
  40. (3)
  41. (1)
  42. (15)
  43. (12)
  44. (20)
  45. (10)
  46. (26)
  47. (1)
  48. (2)
  49. (12)