Agilent HPLC Columns
Whether you are performing conventional or ultra-fast chromatography or analyzing complex basic compounds, Agilent can be trust for the industry’s highest-performing columns that deliver the fast, reproducible results you need – all engineered with Agilent’s unparalleled quality and reliability.
Agilent HPLC Column Material: Polaris
From the collapse-resistant pore structure of the base silica, to the "wettability" engineered into the bonded phases, Polaris columns have been designed for high aqueous conditions. The combination of high phase density bonding, ultra pure silica, and silanol shielding leads to excellent peak shape among polar-modified columns.
Phase |
Particle Size (µm) |
Pore Size (Å) |
PH-Range |
Corbon Loading (%) |
Endcapping |
C18-A |
3, 5, 10 |
180 |
|
13.8 |
Yes |
C18-Ether |
3, 5 |
180 |
|
7.4 |
Yes |
C8 |
3, 5 |
180 |
|
12.1 |
Yes |
NH2 |
3, 5 |
180 |
|
7.1 |
Yes |
Agilent HPLC Column Material: Poroshell
Poroshell columns can achieve high resolution and high speed separation on current instruments, and higher resolution and speed on new high-pressure LC and LC/MS systems. Poroshell columns accelerate customer workflows cost-effectively. The Poroshell columns expand Agilent’s LC column line as a highly-productive, high resolution option, and join the Poroshell 300 columns offered for bioseparations.
Phase |
Particle Size (µm) |
Pore Size (Å) |
PH-Bereich |
Carbon Load (%) |
Endcapping |
SB-C18 |
2.7 |
120 |
1 - 8 |
8 |
No |
EC-C18 |
2.7 |
120 |
2 - 8 |
10 |
double |
EC-C8 |
2.7 |
120 |
2 - 8 |
5 |
double |
Agilent HPLC Column Material: Pursuit
For LC/MS and high throughput applications. Built on the larger 200Å pore size silica, high ligand density delivers up to 40% faster separations without sacrificing resolution. This is accomplished by optimizing mass transfer with the larger pore size.
Phase |
Particle Size (µm) |
Pore Size (Å) |
PH-Range |
Carbon Load (%) |
Endcapping |
C18 |
3, 5, 10 |
200 |
1.5 - 10 |
12.9 |
Yes |
C8 |
3, 5, 10 |
200 |
1.5 - 10 |
7.4 |
Yes |
Diphenyl |
3, 5 |
200 |
1.5 - 8 |
7.3 |
Yes |
PFP |
3, 5 |
200 |
1.5 - 10 |
6.3 |
Yes |
PAH |
3, 5 |
200 |
1.5 - 10 |
|
Yes |
Agilent HPLC Column Material: Pursuit XRS
For performance in analytical R&D, QC and preparative applications. Combining high ligand density with a 100Å high surface area silica, Pursuit XRs columns are designed to increase productivity, as they offer maximum loadability, excellent stability and easy scalability while maintaining superior resolution.
Phase |
Particle Size (µm) |
Pore Size (Å) |
PH-Range |
Carbon Load (%) |
Endcapping |
C18 |
3, 5, 10 |
100 |
1.5 - 10 |
22 |
Yes |
C8 |
3, 5, 10 |
100 |
1.5 - 10 |
15 |
Yes |
Diphenyl |
3, 5 |
100 |
1.5 - 8 |
14.6 |
Yes |
Si |
3, 5, 10 |
100 |
1.5 - 10 |
|
Yes |
Ultra 2.8 C18 |
2.8 |
100 |
1.5 - 10 |
23.2 |
Yes |
Ultra 2.8 C8 |
2.8 |
100 |
1.5 - 10 |
15 |
Yes |
Agilent HPLC Column Material: Zorbax
For normal-phase chromatography, the ZORBAX product line offers a choice of bonded and non-bonded silica packings. Thereby can be choosen between polar (e. g. NH2, CN) and non-polar (e. g. C8, C18) materials.
Phase |
Particle Size (µm) |
Pore Size (Å) |
PH-Range |
Carbon Load (%) |
Endcapping |
Bonus-RP |
1.8, 3.5, 5 |
80 |
2 - 9 |
9.5 |
tripple |
Extend-C18 |
1.8, 3.5, 5 |
80, 300 |
2 - 11.5 |
12.5 |
double |
300Extend-C18 |
3.5, 5 |
300 |
2 - 11.5 |
4 |
double |
RX-C18 |
3.5, 5 |
80 |
2 - 8 |
12 |
No |
RX-C8 |
1.8, 3.5, 5 |
80 |
1 - 8 |
5.5 |
No |
RX-SIL |
1.8, 5 |
80 |
0 - 8 |
|
No |
SIL |
|
70 |
0 - 8 |
7 |
Yes |
NH2 |
5 |
70 |
2 - 7 |
4 |
Yes |
300SCX |
5 |
300 |
2 - 7 |
|
|
HILIC Plus |
3.5 |
95 |
0 - 8 |
|
|
Carbohydrate |
5 |
70 |
2 - 8 |
3.5 |
No |
Eclipse Plus columns provide the ultimate in performance for silica-based columns. Peak shape for the Eclipse Plus is excellent for the most challenging basic compounds, improving efficiency and resolution with these sample types.
Phase |
Particle Size (µm) |
Pore Size (Å) |
PH-Range |
Carbon Load (%) |
Endcapping |
C18 |
1.8, 3.5, 5 |
95 |
2 - 9 |
9 |
double |
C8 |
1.8, 3.5, 5 |
95 |
2 - 9 |
7 |
double |
PAH |
1.8, 3.5, 5 |
95 |
2 - 8 |
14 |
double |
Phenyl-Hexyl |
3.5, 5 |
95 |
2 - 8 |
9 |
double |