Recent developments in LC column technology have now made the use of sub 3 μm particle packing materials practical. These smaller particle size materials allow higher mobile phase linear velocities to be used, without the decrease in separation efficiency experienced with conventional larger particle size packings. This translates into higher throughput and higher productivity. To conserve mobile phase, these sub 3 μm column materials are typically packed into 2.1 mm i.d. columns so that flow rates (mobile phase volume) are kept low. However, smaller sized packings result in elevated operating pressures. Technological advances in pump and injector designs have also kept pace, and these columns can be used at pressures as high as 10,000 psi.The rugged construction of this new line of small particle columns for high pressure application yield excellent longevity and reproducibility. These packings exhibit an exceptionally tight particle size distribution for excellent resolving power and are packed at elevated pressures to assure column stability even at high pressure applications. Each column is tested to ensure the highest level of quality and efficiency in high pressure LC testing.
With Brownlee Superficially Porous Particle (SPP) columns, you can achieve sharper peaks and faster separation results without changing instruments, worrying about high backpressure or compromising column longevity. With their unique particle composition, only Brownlee SPP columns offer you the freedom to push your process farther:
This HPLC column series of Perkin Elmer is the allrounder for conventional HPLC as well as for high-speed HPLC applications. The silica used (110 Å) is equivalent to the packing material Hypersil.
This packing material is especially suitable for separation of large biopolymeres, caused by the wide pore range of this material and by a silica-based producing.
This material is wide-pore silica (300 Å) that is excellent for peptide and protein separation.
This line of columns is made of (60 Å) silica which results in large surface area, high carbon loads, and high retention compounds.
This is a small-pore (80 Å, 5 μm), silica based sorbent for he separation of small molecules. Thereby both monofunctional (comb-pre) and polyfunctional (polymerized loop-type) C8 and C18 sorbents are available.
These HPLC columns are made out of high-purity type B silica with inherent low silanophilic activity. These HPLC columns exhibit excellent peak shape for a wide range of compounds while also having a wide number of phases. The Brownlee Validated columns are the best choice for pharmaceutical applications that deal with a lot of basic or multi-functional compounds.