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VDS optilab HPLC Columns

VDS optilab has been developing chromatography columns, separation phases and accessories in Berlin since 1987. The high quality of the HPLC columns is valued worldwide by companies in the chemical and pharmaceutical industries, universities and authorities. There is a wide range of separation phases such as VDSpher®, VDS optilab polymer phases as well as columns with filling materials from other manufacturers such as ProntoSIL, LiChrospher or Superspher.

VDSpher HPLC Columns are based on spherical silica gels and offer a very wide range of pore sizes and particle diameters to solve all separation problems. VDSpher phases are based on two different basic silica gels: VDSpher Classic and VDSpher PUR. All VDSpher Classic & PUR silica gels are suitable for analytical, semi-preparative and preparative scale. To achieve the best possible column packing, VDSpher PUR phases are a good choice for analytical HPLC and VDSpher Classic phases are especially recommended for preparative chromatography. U-VDSpher columns are ideal for UHPLC applications.

For more information about column materials, please click here.

Items 1-50 of 3661

Product Image of HPLC Column VDSpher PUR 100 C8-M-SE, 3 µm, 4.6 x 150 mm
HPLC Column VDSpher PUR 100 C8-M-SE, 3 µm, 4.6 x 150 mm
Item number: VDVPE08DG046150
Brand: VDS
$506.15
Product Image of HPLC Column VDSpher 100 K-C8, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher 100 K-C8, 5 µm, 4.6 x 60 mm
Item number: VDVDEK08J046060
Brand: VDS
$326.13
Product Image of HPLC Column VDSpher 100 K-C8, 5 µm, 4 x 60 mm
HPLC Column VDSpher 100 K-C8, 5 µm, 4 x 60 mm
Item number: VDVDEK08J040060
Brand: VDS
$326.13
Product Image of HPLC Column VDSpher 100 K-C8, 5 µm, 3 x 60 mm
HPLC Column VDSpher 100 K-C8, 5 µm, 3 x 60 mm
Item number: VDVDEK08J030060
Brand: VDS
$326.13
Product Image of HPLC Column VDSpher 100 K-C8, 3.5 µm, 4.6 x 60 mm
HPLC Column VDSpher 100 K-C8, 3.5 µm, 4.6 x 60 mm
Item number: VDVDEK08H046060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher 100 K-C8, 3.5 µm, 4 x 60 mm
HPLC Column VDSpher 100 K-C8, 3.5 µm, 4 x 60 mm
Item number: VDVDEK08H040060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher 100 K-C8, 3.5 µm, 3 x 60 mm
HPLC Column VDSpher 100 K-C8, 3.5 µm, 3 x 60 mm
Item number: VDVDEK08H030060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher 100 K-C18, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher 100 K-C18, 5 µm, 4.6 x 60 mm
Item number: VDVDEK18J046060
Brand: VDS
$326.13
Product Image of HPLC Column VDSpher 100 K-C18, 5 µm, 4 x 60 mm
HPLC Column VDSpher 100 K-C18, 5 µm, 4 x 60 mm
Item number: VDVDEK18J040060
Brand: VDS
$326.13
Product Image of HPLC Column VDSpher 100 K-C18, 5 µm, 3 x 60 mm
HPLC Column VDSpher 100 K-C18, 5 µm, 3 x 60 mm
Item number: VDVDEK18J030060
Brand: VDS
$326.13
Product Image of HPLC Column VDSpher 100 K-C18, 3.5 µm, 4.6 x 60 mm
HPLC Column VDSpher 100 K-C18, 3.5 µm, 4.6 x 60 mm
Item number: VDVDEK18H046060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher 100 K-C18, 3.5 µm, 4 x 60 mm
HPLC Column VDSpher 100 K-C18, 3.5 µm, 4 x 60 mm
Item number: VDVDEK18H040060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher 100 K-C18, 3.5 µm, 3 x 60 mm
HPLC Column VDSpher 100 K-C18, 3.5 µm, 3 x 60 mm
Item number: VDVDEK18H030060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher HypRep BDS-C18, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher HypRep BDS-C18, 5 µm, 4.6 x 60 mm
Item number: VDVRHB18J046060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher HypRep BDS-C18, 5 µm, 4 x 60 mm
HPLC Column VDSpher HypRep BDS-C18, 5 µm, 4 x 60 mm
Item number: VDVRHB18J040060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher HypRep BDS-C18, 5 µm, 3 x 60 mm
HPLC Column VDSpher HypRep BDS-C18, 5 µm, 3 x 60 mm
Item number: VDVRHB18J030060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher HypRep BDS-C18, 3 µm, 4.6 x 60 mm
HPLC Column VDSpher HypRep BDS-C18, 3 µm, 4.6 x 60 mm
Item number: VDVRHB18G046060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher HypRep BDS-C18, 3 µm, 4 x 60 mm
HPLC Column VDSpher HypRep BDS-C18, 3 µm, 4 x 60 mm
Item number: VDVRHB18G040060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher HypRep BDS-C18, 3 µm, 3 x 60 mm
HPLC Column VDSpher HypRep BDS-C18, 3 µm, 3 x 60 mm
Item number: VDVRHB18G030060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher HypRep ODS, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher HypRep ODS, 5 µm, 4.6 x 60 mm
Item number: VDVRHF18J046060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher HypRep ODS, 5 µm, 4 x 60 mm
HPLC Column VDSpher HypRep ODS, 5 µm, 4 x 60 mm
Item number: VDVRHF18J040060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher HypRep ODS, 5 µm, 3 x 60 mm
HPLC Column VDSpher HypRep ODS, 5 µm, 3 x 60 mm
Item number: VDVRHF18J030060
Brand: VDS
$352.22
Product Image of HPLC Column VDSpher HypRep ODS, 3 µm, 4.6 x 60 mm
HPLC Column VDSpher HypRep ODS, 3 µm, 4.6 x 60 mm
Item number: VDVRHF18G046060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher HypRep ODS, 3 µm, 4 x 60 mm
HPLC Column VDSpher HypRep ODS, 3 µm, 4 x 60 mm
Item number: VDVRHF18G040060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher HypRep ODS, 3 µm, 3 x 60 mm
HPLC Column VDSpher HypRep ODS, 3 µm, 3 x 60 mm
Item number: VDVRHF18G030060
Brand: VDS
$378.31
Product Image of HPLC Column VDSpher CSM C18-M-SE, 2.5 µm, 4.6 x 60 mm
HPLC Column VDSpher CSM C18-M-SE, 2.5 µm, 4.6 x 60 mm
Item number: VDVCX18DF046060
Brand: VDS
$587.03
Product Image of HPLC Column VDSpher CSM C18-M-SE, 2.5 µm, 4 x 60 mm
HPLC Column VDSpher CSM C18-M-SE, 2.5 µm, 4 x 60 mm
Item number: VDVCX18DF040060
Brand: VDS
$587.03
Product Image of HPLC Column VDSpher CSM C18-M-SE, 2.5 µm, 3 x 60 mm
HPLC Column VDSpher CSM C18-M-SE, 2.5 µm, 3 x 60 mm
Item number: VDVCX18DF030060
Brand: VDS
$587.03
Product Image of HPLC Column VDSpher CSM C18-AQ, 2.5 µm, 4.6 x 60 mm
HPLC Column VDSpher CSM C18-AQ, 2.5 µm, 4.6 x 60 mm
Item number: VDVCX184F046060
Brand: VDS
$587.03
Product Image of HPLC Column VDSpher CSM C18-AQ, 2.5 µm, 4 x 60 mm
HPLC Column VDSpher CSM C18-AQ, 2.5 µm, 4 x 60 mm
Item number: VDVCX184F040060
Brand: VDS
$587.03
Product Image of HPLC Column VDSpher CSM C18-AQ, 2.5 µm, 3 x 60 mm
HPLC Column VDSpher CSM C18-AQ, 2.5 µm, 3 x 60 mm
Item number: VDVCX184F030060
Brand: VDS
$587.03
Product Image of HPLC Column VDSpher CSM C18-E, 2.5 µm, 4.6 x 60 mm
HPLC Column VDSpher CSM C18-E, 2.5 µm, 4.6 x 60 mm
Item number: VDVCX181F046060
Brand: VDS
$587.03
Product Image of HPLC Column VDSpher CSM C18-E, 2.5 µm, 4 x 60 mm
HPLC Column VDSpher CSM C18-E, 2.5 µm, 4 x 60 mm
Item number: VDVCX181F040060
Brand: VDS
$587.03
Product Image of HPLC Column VDSpher CSM C18-E, 2.5 µm, 3 x 60 mm
HPLC Column VDSpher CSM C18-E, 2.5 µm, 3 x 60 mm
Item number: VDVCX181F030060
Brand: VDS
$587.03
Product Image of UHPLC Column U-VDSpher PUR Phenyl-E, 1.8 µm, 4.6 x 60 mm
UHPLC Column U-VDSpher PUR Phenyl-E, 1.8 µm, 4.6 x 60 mm
Item number: VDUVE051C046060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR Phenyl-E, 1.8 µm, 4 x 60 mm
UHPLC Column U-VDSpher PUR Phenyl-E, 1.8 µm, 4 x 60 mm
Item number: VDUVE051C040060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR Phenyl-E, 1.8 µm, 3 x 60 mm
UHPLC Column U-VDSpher PUR Phenyl-E, 1.8 µm, 3 x 60 mm
Item number: VDUVE051C030060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-SE, 1.8 µm, 4.6 x 60 mm
UHPLC Column U-VDSpher PUR C18-SE, 1.8 µm, 4.6 x 60 mm
Item number: VDUVE18BC046060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-SE, 1.8 µm, 4 x 60 mm
UHPLC Column U-VDSpher PUR C18-SE, 1.8 µm, 4 x 60 mm
Item number: VDUVE18BC040060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-SE, 1.8 µm, 3 x 60 mm
UHPLC Column U-VDSpher PUR C18-SE, 1.8 µm, 3 x 60 mm
Item number: VDUVE18BC030060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-M-SE, 1.8 µm, 4.6 x 60 mm
UHPLC Column U-VDSpher PUR C18-M-SE, 1.8 µm, 4.6 x 60 mm
Item number: VDUVE18DC046060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-M-SE, 1.8 µm, 4 x 60 mm
UHPLC Column U-VDSpher PUR C18-M-SE, 1.8 µm, 4 x 60 mm
Item number: VDUVE18DC040060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-M-SE, 1.8 µm, 3 x 60 mm
UHPLC Column U-VDSpher PUR C18-M-SE, 1.8 µm, 3 x 60 mm
Item number: VDUVE18DC030060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-H, 1.8 µm, 4.6 x 60 mm
UHPLC Column U-VDSpher PUR C18-H, 1.8 µm, 4.6 x 60 mm
Item number: VDUVE184C046060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-H, 1.8 µm, 4 x 60 mm
UHPLC Column U-VDSpher PUR C18-H, 1.8 µm, 4 x 60 mm
Item number: VDUVE184C040060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-H, 1.8 µm, 3 x 60 mm
UHPLC Column U-VDSpher PUR C18-H, 1.8 µm, 3 x 60 mm
Item number: VDUVE184C030060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-E, 1.8 µm, 4.6 x 60 mm
UHPLC Column U-VDSpher PUR C18-E, 1.8 µm, 4.6 x 60 mm
Item number: VDUVE181C046060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-E, 1.8 µm, 4 x 60 mm
UHPLC Column U-VDSpher PUR C18-E, 1.8 µm, 4 x 60 mm
Item number: VDUVE181C040060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR C18-E, 1.8 µm, 3 x 60 mm
UHPLC Column U-VDSpher PUR C18-E, 1.8 µm, 3 x 60 mm
Item number: VDUVE181C030060
Brand: VDS
$790.53
Product Image of UHPLC Column U-VDSpher PUR SIL, 1.8 µm, 4.6 x 60 mm
UHPLC Column U-VDSpher PUR SIL, 1.8 µm, 4.6 x 60 mm
Item number: VDUVE000C046060
Brand: VDS
$790.53

Items 1-50 of 3661

VDSpher PUR and VDSpher Classic 

VDSpher phases by optilab are based on two different basic silica gels: VDSpher Classic & PUR, which differ mainly in their purity. The purity of the basic silica gel has a significant impact on the chromatographic separation because the metal content changes the properties of the silica gel and the surface. Hence, the interactions between the metal parts and the electron-rich analytes need to be considered. Due to the higher metal content of the VDSpher Classic 100 C18-E phase the analytes were retarded much stronger as compared to VDSpher PUR 100 C18-E.

All VDSpher Classic & PUR silica gels are suitable for analytical, semi-preparative and preparative scale. To achieve the best possible column packing, VDSpher PUR phases are recommended for analytical issues and VDSpher Classic phases for preparative purposes.

Normally, the standard phase VDSpher PUR 100 C18-E is a good starting point for many separations, e. g. for the isolation of natural substances, for the determination of caffeine in coffee or tea and even for the determination of amino acids. VDSpher PUR 100 C18-E is of medium hydrophobicity and shows a low silanophilic activity.

VDSpher MS Phases

Columns of smaller dimensions are usually preferred in LC/MS analysis. To profit from a high resolution, silica gel with a small particle size is recommended for the column. Generally, any VDSpher column can be used for LC/MS. Mass spectrometry is a particularly sensitive detection method and displays very low impurities, e.g. carry-overs from previous runs (“carry-over effect“). VDSpher MS phases are designed specially to avoid these effects.

VDSpher OptiAqua and VDSpher OptiAqua PUR 

VDSpher OptiAqua phases are ideally suited for very hydrophilic applications. A special polar endcapping makes it possible to use 100% water as a solvent while still maintaining reversed phase properties. 

On the basis of VDSpher Classic & PUR, six VDSpher OptiAqua phases with different modifications as well as pore sizes and particle diameters have been developed. With these phases, numerous applications can be performed in preparative as well as analytical HPLC. Also, analytes of different sizes can be handled optimally. Thus, different molar mass ranges can be covered, depending on the pore size of the modified silica gel. 

VDSpher OptiAqua phases can be used e.g. to separate polar substances. Typical analytes are antibiotics, biomolecules, drugs, nucleobases, organic acids, parabens, pesticides, sulfonamides, water-soluble vitamins and xanthines.

All VDSpher OptiAqua phases are pH-stable in a range of 2 to 7.5 and can be used without any problem up to a temperature of 60 °C.

VDSpher OptiBio and VDSpher OptiBio PUR

VDSpher OptiBio have been developed for biochemical analysis such as protein and peptide separation. Numerous separation phases with different modifications, pore sizes and particle diameters are available. With VDSpher OptiBio columns e. g. antibodies, oligo-nucleotides, peptides and proteins as well as other biomolecules can be examined.

All VDSpher OptiBio modifications are pH-stable over a large range and can be used without any problem up to a temperature of 65 °C.