VDS optilab HPLC Columns

VDSpher HPLC Columns - made in Germany

VDSpher HPLC Columns by the German manufacturer VDS optilab are based on spherical silica gels and offer a very wide range of pore sizes and particle diameters to solve all separation problems. VDSpher phases are based on two different basic silica gels: VDSpher Classic and VDSpher PUR. All VDSpher Classic & PUR silica gels are suitable for analytical, semi-preparative and preparative scale. To achieve the best possible column packing, VDSpher PUR phases are a good choice for analytical HPLC and VDSpher Classic phases are especially recommended for preparative chromatography. U-VDSpher columns are ideal for UHPLC applications. 

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Product Image of HPLC Column VDSpher PUR C18-M, 3 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-M, 3 µm, 4.6 x 60 mm
Item number: VDVPE189G046060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C18-M, 3 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-M, 3 µm, 4 x 60 mm
Item number: VDVPE189G040060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C18-M, 3 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-M, 3 µm, 3 x 60 mm
Item number: VDVPE189G030060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C18-H, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-H, 5 µm, 4.6 x 60 mm
Item number: VDVPE184J046060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-H, 5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-H, 5 µm, 4 x 60 mm
Item number: VDVPE184J040060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-H, 5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-H, 5 µm, 3 x 60 mm
Item number: VDVPE184J030060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-H, 4 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-H, 4 µm, 4.6 x 60 mm
Item number: VDVPE184I046060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-H, 4 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-H, 4 µm, 4 x 60 mm
Item number: VDVPE184I040060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-H, 4 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-H, 4 µm, 3 x 60 mm
Item number: VDVPE184I030060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-H, 3.5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-H, 3.5 µm, 4.6 x 60 mm
Item number: VDVPE184H046060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-H, 3.5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-H, 3.5 µm, 4 x 60 mm
Item number: VDVPE184H040060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-H, 3.5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-H, 3.5 µm, 3 x 60 mm
Item number: VDVPE184H030060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-H, 3 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-H, 3 µm, 4.6 x 60 mm
Item number: VDVPE184G046060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C18-H, 3 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-H, 3 µm, 4 x 60 mm
Item number: VDVPE184G040060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C18-H, 3 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-H, 3 µm, 3 x 60 mm
Item number: VDVPE184G030060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C18-E, 10 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-E, 10 µm, 4.6 x 60 mm
Item number: VDVPE181N046060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-E, 10 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-E, 10 µm, 4 x 60 mm
Item number: VDVPE181N040060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-E, 10 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-E, 10 µm, 3 x 60 mm
Item number: VDVPE181N030060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-E, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-E, 5 µm, 4.6 x 60 mm
Item number: VDVPE181J046060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-E, 5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-E, 5 µm, 4 x 60 mm
Item number: VDVPE181J040060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-E, 5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-E, 5 µm, 3 x 60 mm
Item number: VDVPE181J030060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C18-E, 4 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-E, 4 µm, 4.6 x 60 mm
Item number: VDVPE181I046060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-E, 4 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-E, 4 µm, 4 x 60 mm
Item number: VDVPE181I040060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-E, 4 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-E, 4 µm, 3 x 60 mm
Item number: VDVPE181I030060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-E, 3.5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-E, 3.5 µm, 4.6 x 60 mm
Item number: VDVPE181H046060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-E, 3.5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-E, 3.5 µm, 4 x 60 mm
Item number: VDVPE181H040060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-E, 3.5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-E, 3.5 µm, 3 x 60 mm
Item number: VDVPE181H030060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C18-E, 3 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C18-E, 3 µm, 4.6 x 60 mm
Item number: VDVPE181G046060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C18-E, 3 µm, 4 x 60 mm
HPLC Column VDSpher PUR C18-E, 3 µm, 4 x 60 mm
Item number: VDVPE181G040060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C18-E, 3 µm, 3 x 60 mm
HPLC Column VDSpher PUR C18-E, 3 µm, 3 x 60 mm
Item number: VDVPE181G030060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C8-SE, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C8-SE, 5 µm, 4.6 x 60 mm
Item number: VDVPE08BJ046060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-SE, 5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C8-SE, 5 µm, 4 x 60 mm
Item number: VDVPE08BJ040060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-SE, 5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C8-SE, 5 µm, 3 x 60 mm
Item number: VDVPE08BJ030060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-SE, 3.5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C8-SE, 3.5 µm, 3 x 60 mm
Item number: VDVPE08BH030060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C8-SE, 3.5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C8-SE, 3.5 µm, 4 x 60 mm
Item number: VDVPE08BH040060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C8-SE, 3.5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C8-SE, 3.5 µm, 4.6 x 60 mm
Item number: VDVPE08BH046060
Brand: VDS
$456.00
Product Image of HPLC Column VDSpher PUR C8-SE, 3 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C8-SE, 3 µm, 4.6 x 60 mm
Item number: VDVPE08BG046060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C8-SE, 3 µm, 4 x 60 mm
HPLC Column VDSpher PUR C8-SE, 3 µm, 4 x 60 mm
Item number: VDVPE08BG040060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C8-SE, 3 µm, 3 x 60 mm
HPLC Column VDSpher PUR C8-SE, 3 µm, 3 x 60 mm
Item number: VDVPE08BG030060
Brand: VDS
$540.00
Product Image of HPLC Column VDSpher PUR C8-NE, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C8-NE, 5 µm, 4.6 x 60 mm
Item number: VDVPE08EJ046060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-NE, 5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C8-NE, 5 µm, 4 x 60 mm
Item number: VDVPE08EJ040060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-NE, 5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C8-NE, 5 µm, 3 x 60 mm
Item number: VDVPE08EJ030060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-M-E, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C8-M-E, 5 µm, 4.6 x 60 mm
Item number: VDVPE082J046060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-M-E, 5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C8-M-E, 5 µm, 4 x 60 mm
Item number: VDVPE082J040060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-M-E, 5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C8-M-E, 5 µm, 3 x 60 mm
Item number: VDVPE082J030060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-M-II, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C8-M-II, 5 µm, 4.6 x 60 mm
Item number: VDVPE089J046060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-M-II, 5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C8-M-II, 5 µm, 4 x 60 mm
Item number: VDVPE089J040060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-M-II, 5 µm, 3 x 60 mm
HPLC Column VDSpher PUR C8-M-II, 5 µm, 3 x 60 mm
Item number: VDVPE089J030060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-H, 5 µm, 4.6 x 60 mm
HPLC Column VDSpher PUR C8-H, 5 µm, 4.6 x 60 mm
Item number: VDVPE084J046060
Brand: VDS
$420.00
Product Image of HPLC Column VDSpher PUR C8-H, 5 µm, 4 x 60 mm
HPLC Column VDSpher PUR C8-H, 5 µm, 4 x 60 mm
Item number: VDVPE084J040060
Brand: VDS
$420.00

VDSpher PUR and VDSpher Classic 

VDSpher phases by optilab are based on two different basic silica gels: VDSpher Classic & PUR, which differ mainly in their purity. The purity of the basic silica gel has a significant impact on the chromatographic separation because the metal content changes the properties of the silica gel and the surface. Hence, the interactions between the metal parts and the electron-rich analytes need to be considered. Due to the higher metal content of the VDSpher Classic 100 C18-E phase the analytes were retarded much stronger as compared to VDSpher PUR 100 C18-E.

All VDSpher Classic & PUR silica gels are suitable for analytical, semi-preparative and preparative scale. To achieve the best possible column packing, VDSpher PUR phases are recommended for analytical issues and VDSpher Classic phases for preparative purposes.

Normally, the standard phase VDSpher PUR 100 C18-E is a good starting point for many separations, e. g. for the isolation of natural substances, for the determination of caffeine in coffee or tea and even for the determination of amino acids. VDSpher PUR 100 C18-E is of medium hydrophobicity and shows a low silanophilic activity.

VDSpher MS Phases

Columns of smaller dimensions are usually preferred in LC/MS analysis. To profit from a high resolution, silica gel with a small particle size is recommended for the column. Generally, any VDSpher column can be used for LC/MS. Mass spectrometry is a particularly sensitive detection method and displays very low impurities, e.g. carry-overs from previous runs (“carry-over effect“). VDSpher MS phases are designed specially to avoid these effects.

VDSpher OptiAqua and VDSpher OptiAqua PUR 

VDSpher OptiAqua phases are ideally suited for very hydrophilic applications. A special polar endcapping makes it possible to use 100% water as a solvent while still maintaining reversed phase properties. 

On the basis of VDSpher Classic & PUR, six VDSpher OptiAqua phases with different modifications as well as pore sizes and particle diameters have been developed. With these phases, numerous applications can be performed in preparative as well as analytical HPLC. Also, analytes of different sizes can be handled optimally. Thus, different molar mass ranges can be covered, depending on the pore size of the modified silica gel. 

VDSpher OptiAqua phases can be used e.g. to separate polar substances. Typical analytes are antibiotics, biomolecules, drugs, nucleobases, organic acids, parabens, pesticides, sulfonamides, water-soluble vitamins and xanthines.

All VDSpher OptiAqua phases are pH-stable in a range of 2 to 7.5 and can be used without any problem up to a temperature of 60 °C.

VDSpher OptiBio and VDSpher OptiBio PUR

VDSpher OptiBio have been developed for biochemical analysis such as protein and peptide separation. Numerous separation phases with different modifications, pore sizes and particle diameters are available. With VDSpher OptiBio columns e. g. antibodies, oligo-nucleotides, peptides and proteins as well as other biomolecules can be examined.

All VDSpher OptiBio modifications are pH-stable over a large range and can be used without any problem up to a temperature of 65 °C.