HPLC Column Avanti BDS QUATTRO, 3 µm, 4,6 x 50mm

A polar embedded phase that gives excellent peak shape and low retention for difficult bases at pH 7. Acids, bases and chelates are readily eluted as sharp peaks at pH 2 using TFA.

The Avanti BDS reversed phases (C8 and C18) offer a conventional approach to the separation of polar compounds by providing a base deactivated silica and a monomerically bonded linear alkyl functional group. This combination gives excellent performance at low pH but can show some slight tailing with difficult bases at neutral pH. The ultimate performance of these phases was constrained by the need to offer a close alternative to current BDS media.

Polar embedded phases have become a popular approach to improving peak shape with difficult compounds but with the added advantage of delivering alternative selectivity to standard alkyl phases. Rather than just improve the performance of the BDS C18 phase, we decided to incorporate the additional benefits offered by a polar embedded phases.