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Syringe filters are designed for filtering the sample solution before injection. These are usually membrane filters made of the appropriate materials. However, they are also available as glass fiber filters or, in cases where a glass fiber filter is required upstream of the membrane filter, as membrane filters with glass fiber pre-filters. When selecting syringe filters, materials of the highest quality should be used as the sensitivity of the analytical method increases. These are specially tested for interfering substances. In addition, they guarantee a high batch consistency for steady, reliable analytical results.

At Analytics-Shop you will find syringe filters from renowned manufacturers such as Whatman, ThermoFisher, Macherey-Nagel etc. as well as the inexpensive alternatives of our own Altmann brand. Use the drop-down menu on the left side of the page to simplify your search for suitable syringe filters.

Here you will find a more detailed description of the products.

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Syringe Filters

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Properties of Syringe Filters

The properties of syringe filters made from different materials are extremely verifying. Therefore, the choice of the filter especially depends on the chemicals used for synthesis.

The following table provides an overview of the most common materials for syringe filters combined with the acronyms, the application areas as well as the chemical resistance of each synthetic.

Specific Properties   Application Areas
Cellulose Acetate (CA)   Low protein absorbtion, especially suited for steril filtration and clarification of aqueous solutions, culture media, buffers and serums. Good chemical resistance versus alcoholics and oils with a pH range from 4 to 8. This hydrophilic membrane is characterized by excellent flow trough and extraordinary temperature stability up to 180° C.
Cellulose Nitrate (CN)   Cellulose nitrate membranes are standard membranes for analytical and microbiological membrane filtration. These filters are available in many different pore sizes to cover various application areas like water, food or drink analysis. Chemical resistance versus aqueous solutions with a pH from 4 to 8, carbon hydrates or organic solvents is guaranteed up 130° C.
Polyamide (PA)   Hydrophilic membranes that can be used several times for filtration of aqueous or organic solvents and aqueous solutions with a pH ranging from 3 to 14. Especially suited for steril filtration and clarification due to low amount of extractables.
Polycarbonate (PC)   Membranes made from polycarbonate are characterized by a uniform, round pore structure for the whole membrane. Particles can be identified easily due to the high contrast to the smooth surface.
Polytetrafluoroethylene (PTFE)   Permanently hydrophobic filter material, perfectly applicable for air and gas as well as non-polar liquids. PTFE membranes are characterized by an extraordinary chemical resistance versus nearly all chemicals and are suited for both filtration of acids or aggressive solvents and particle filtration of air or water samples up to 200° C.
Regenerated Cellulose (RC)   Regenerated cellulose membranes are solvent resistent and hydrophilic. 0.45 µm pore sizes are mainly used for HPLC sample preparation. This membrane type is resistent versus most solvents, as well as aqueous solutions with a pH from 3 to 12 and temperature stable up to 200° C.


Pore Sizes and Volumes

The filter size especially depends on the filtration volume. For small volumes (< 1 ml) syringe filters with a diameter of 3 mm are being used, for medium volumes (1-10 ml) 15 mm and for large volumes (> 10 ml) 25 mm. Common pore sizes for UHPLC and HPLC columns with small particle sizes (< 3 µm) are 0.2 and for columns with larger particle sizes (> 3.5 µm) 0.45 µm, respectively. The pore sizes available range from sub µm up to 10 µm.The following tables give an overview about the different filter types and the specific lables of each producer.

Syringe Filter Comparison Chart

Material Whatman Sartorius Pall Millipore
CA Puradisc CA Minisart NML    
GF Whatman GD/X Minisart GF Acrodisc GF  
PA Puradisc PA Minisart NY Acrodisc PA Millex
PES Puradisc PES Minisart PES Acrodisc PES Millipore Express
PTFE Puradisc PTFE Minisart SRP Acrodisc PTFE Millipore LCR
PVDF Puradisc PVDF   Acrodisc PVDF Durapore
RC Whatman Spartan Minisart RC