Use Thermo Scientific™ ProPac™ WCX-10 LC columns and achieve exceptionally high resolution for the separation of proteins with their variants. ProPac columns are based on stationary phases of non-porous 10 µm polymer beads and resolve isoforms that differ in only a single charged residue. A thin, hydrophilic layer grafted onto the particle core eliminates unwanted secondary interactions. The cation exchange surface provides pH-based selectivity control and rapid mass transfer for highly efficient separation and moderate capacity.