HPLC Guard Columns

Precolumns (guard columns) and precolumn cartridges for HPLC

Separation columns with modern solid phases are critical components of the HPLC system. Careful handling and protection against impurities is necessary to ensure optimum and consistent separation results. In order to extend the life of your HPLC columns, it is advisable to use guard columns. They are able to remove molecules which would form an irreversible bond with the material of the analytical column. Guard coloumns need to be changed on a regular basis. A good indication on when to change a precolumn is a gradual increase in the back pressure. For more information on the storage and maintenance of HPLC column, click here.

We carry a wide range of solid phase and stainless steel cartridges for HPLC and UHPLC.

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Product Image of Universal Reversed Phase (RP) PreColumn Cartridge 5x2mm for Columns with 2 mm ID, 5/PAK
Universal Reversed Phase (RP) PreColumn Cartridge 5x2mm for Columns with 2 mm ID, 5/PAK
Item number: AAVRP-500520-5
Brand: Altmann Analytik

In stock

$280.00
Product Image of Universal Reversed Phase (RP) PreColumn Cartridge 20x4mm for Columns with 3, 4 and 4,6 mm ID, 5/PAK
Universal Reversed Phase (RP) PreColumn Cartridge 20x4mm for Columns with 3, 4 and 4,6 mm ID, 5/PAK
Item number: AAVRP-201040-5
Brand: Altmann Analytik

In stock

$330.00
Product Image of HPLC Guard Column Nucleosil 100 C18, 5.0 µm, 4 x 10 mm, 5pc/PAK
HPLC Guard Column Nucleosil 100 C18, 5.0 µm, 4 x 10 mm, 5pc/PAK
Item number: AAVNS1C9-501040-5
Brand: Altmann Analytik
$240.00
Product Image of HPLC Guard Column Holder indirect, 5 x 4 mm
HPLC Guard Column Holder indirect, 5 x 4 mm
Item number: AAHI-00540
Brand: Altmann Analytik

In stock

$151.20
Product Image of HPLC Guard Column Holder indirect, 10 x 4,6 mm
HPLC Guard Column Holder indirect, 10 x 4,6 mm
Item number: AAHI-01046
Brand: Altmann Analytik

In stock

$158.40
Product Image of HPLC Guard Column Holder indirect, 10 x 4 mm
HPLC Guard Column Holder indirect, 10 x 4 mm
Item number: AAHI-01040
Brand: Altmann Analytik

In stock

$158.40
Product Image of HPLC Guard Column Holder indirect, 10 x 3 mm
HPLC Guard Column Holder indirect, 10 x 3 mm
Item number: AAHI-01030
Brand: Altmann Analytik

In stock

$158.40
Product Image of HPLC Guard MaxPeak Premier Protein SEC, 250Å, 2.5 µm, 4.6 x 30 mm
HPLC Guard MaxPeak Premier Protein SEC, 250Å, 2.5 µm, 4.6 x 30 mm
Item number: WT186009969
Brand: Waters
$420.00
Product Image of HPLC Column EC 4/3 NUCLEOSIL 100-5 C18
HPLC Column EC 4/3 NUCLEOSIL 100-5 C18
Item number: MN721074.30
Brand: Macherey-Nagel
$189.00
Product Image of HPLC Guard Column Starter Kit, PRP-X300, 12-20 µm, 4.6 x 20 mm, 1 Holder, 1 Cartridge
HPLC Guard Column Starter Kit, PRP-X300, 12-20 µm, 4.6 x 20 mm, 1 Holder, 1 Cartridge
Item number: HT79129
Brand: Hamilton
$270.20
Product Image of HPLC Guard Column Genesis 4µm C8 (for 3.0 - 4.6mm id) 3pk, old no: FH1962-2
HPLC Guard Column Genesis 4µm C8 (for 3.0 - 4.6mm id) 3pk, old no: FH1962-2
Item number: GR5169666
Brand: Avantor

In stock

Product Image of HPLC Guard Cartridge Vydac 214TP 5µm C4 (for 3.0 - 4.6mm id) 2pk, old no: 214GD54, new no: 5103877/N
HPLC Guard Cartridge Vydac 214TP 5µm C4 (for 3.0 - 4.6mm id) 2pk, old no: 214GD54, new no: 5103877/N
Item number: GR5103877
Brand: Avantor

In stock

$600.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC87511
Brand: Chiral
$425.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IG, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IG, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC87311
Brand: Chiral
$360.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IF-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IF-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC86511
Brand: Chiral
$425.00
Product Image of HPLC Guard Cartridge CHIRALPAK IF, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK IF, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC86311
Brand: Chiral
$360.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IE-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IE-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC85511
Brand: Chiral
$425.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IE, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IE, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC85311
Brand: Chiral
$360.00
Product Image of HPLC Guard Cartridge CHIRALPAK® ID-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® ID-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC84511
Brand: Chiral
$425.00
Product Image of HPLC Guard Cartridge CHIRALPAK® ID, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® ID, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC84311
Brand: Chiral
$360.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IC-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IC-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC83511
Brand: Chiral
$425.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IC, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IC, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC83311
Brand: Chiral
$360.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IB-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IB-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC81511
Brand: Chiral
$425.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IB, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IB, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC81311
Brand: Chiral
$360.00
Product Image of HPLC Guard Cartridge CHIRALPAK IA-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK IA-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC80511
Brand: Chiral
$425.00
Product Image of HPLC Guard Cartridge CHIRALPAK IA, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK IA, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC80311
Brand: Chiral
$360.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AY-RH, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AY-RH, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC47711
Brand: Chiral
$350.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AY-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AY-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC47511
Brand: Chiral
$415.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AY-H, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AY-H, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC47311
Brand: Chiral
$350.00
Product Image of HPLC  Guard Cartridge CHIRALCEL® OZ-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALCEL® OZ-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC42511
Brand: Chiral
$415.00
Product Image of HPLC  Guard Cartridge CHIRALCEL® OZ-H, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALCEL® OZ-H, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC42311
Brand: Chiral
$350.00
Product Image of HPLC Guard Cartridge CHIRALPAK® HSA, 10 x 2 mm, 5 µm,  2 pc/pak
HPLC Guard Cartridge CHIRALPAK® HSA, 10 x 2 mm, 5 µm, 2 pc/pak
Item number: DAIC34791
Brand: Chiral
$340.00
Product Image of HPLC Guard Cartridge CHIRALPAK® HSA, 10 x 3 mm, 5 µm,  2 pc/pak
HPLC Guard Cartridge CHIRALPAK® HSA, 10 x 3 mm, 5 µm, 2 pc/pak
Item number: DAIC34781
Brand: Chiral
$340.00
Product Image of HPLC Guard Cartridge CHIRALPAK® HSA, 10 x 4 mm, 5 µm,  2 pc/pak
HPLC Guard Cartridge CHIRALPAK® HSA, 10 x 4 mm, 5 µm, 2 pc/pak
Item number: DAIC34711
Brand: Chiral
$415.00
Product Image of HPLC Guard Cartridge CHIRALPAK® CBH, 10 x 2 mm, 5 µm,  2 pc/pak
HPLC Guard Cartridge CHIRALPAK® CBH, 10 x 2 mm, 5 µm, 2 pc/pak
Item number: DAIC33791
Brand: Chiral
$395.00
Product Image of HPLC Guard Cartridge CHIRALPAK® CBH, 10 x 3 mm, 5 µm,  2 pc/pak
HPLC Guard Cartridge CHIRALPAK® CBH, 10 x 3 mm, 5 µm, 2 pc/pak
Item number: DAIC33781
Brand: Chiral
$395.00
Product Image of HPLC Guard Cartridge CHIRALPAK® CBH, 10 x 4 mm, 5 µm,  2 pc/pak
HPLC Guard Cartridge CHIRALPAK® CBH, 10 x 4 mm, 5 µm, 2 pc/pak
Item number: DAIC33711
Brand: Chiral
$465.00
Product Image of HPLC Guard Cartridge CHIRALPAK QN-AX, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK QN-AX, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC32311
Brand: Chiral
$395.00
Product Image of HPLC Guard Cartridge CHIRALPAK® QD-AX, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® QD-AX, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC31311
Brand: Chiral
$395.00
Product Image of HPLC Guard CHIRALPAK AGP, 10 x 2 mm, 5 µm, 2 pc/pak
HPLC Guard CHIRALPAK AGP, 10 x 2 mm, 5 µm, 2 pc/pak
Item number: DAIC30791
Brand: Chiral
$395.00
Product Image of HPLC Guard CHIRALPAK AGP, 10 x 3 mm, 5 µm, 2 pc/pak
HPLC Guard CHIRALPAK AGP, 10 x 3 mm, 5 µm, 2 pc/pak
Item number: DAIC30781
Brand: Chiral
$395.00
Product Image of HPLC Guard CHIRALPAK AGP, 10 x 4 mm, 5 µm, 2 pc/pak
HPLC Guard CHIRALPAK AGP, 10 x 4 mm, 5 µm, 2 pc/pak
Item number: DAIC30711
Brand: Chiral
$465.00
Product Image of HPLC Guard Column CROWNPAK CR, 10 x 4 mm, 5 µm
HPLC Guard Column CROWNPAK CR, 10 x 4 mm, 5 µm
Item number: DAIC27711
Brand: Chiral
$290.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AS-3R, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AS-3R, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC20811
Brand: Chiral
$415.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AS-RH, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AS-RH, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC20711
Brand: Chiral
$350.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AS-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AS-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC20511
Brand: Chiral
$415.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AS-H, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AS-H, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC20311
Brand: Chiral
$350.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AD-3R, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AD-3R, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC19811
Brand: Chiral
$320.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AD-RH, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AD-RH, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC19711
Brand: Chiral
$270.00
Product Image of HPLC Guard Cartridge CHIRALPAK® AD-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® AD-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC19511
Brand: Chiral
$320.00

If you want to protect your column from contamination by connecting a precolumn cartridge upstream, you always need a precolumn holder as well. At Analytics-Shop you will find HPLC precolumns from all well-known manufacturers, from Agilent Technologies and Chiral to Macherey-Nagel, Merck, Thermo Scientific, Waters and Whatman. High quality and at the same time very affordable alternatives of precolumns and columns are products of our house brand Altmann Analytik.

Indirect pre-column holders are compatible with the common columns of all manufacturers. For this you need an additional column connector as an intermediate piece between column and pre-column holder. The following graphic shows the connection possibilities if you need a pre-column for an HPLC column (column connectors must be ordered separately):

 

In general, the length of the precolumn should not exceed 10 percent of the column. We therefore recommend

- for columns with length up to 50 mm: precolumns with length 5 mm
- for columns with length from 60 mm to 199 mm: precolumns with length 10 mm
- for columns with length of 200 mm and larger: precolumns with length 20 mm