What is column chromatography?

Column chromatography chromatography is particularly useful for separating large amounts of material. The column is a glass tube filled with a stationary phase. The stationary phase can be silica gel or cellulose. Depending on their chemical nature, the different compounds of the mixture interact well or less well with this stationary phase and are eluted in different fractions.

The most important field in column chromatography is HPLC.