The XSelect Premier HSS C18 Columns contain an ultra-performance general purpose C18 bonded phase that provides increased retention (vs. XBridge BEH C18 columns). The high strength silica (HSS) particle and tri-functional C18 bonded phase provide extremely long column lifetimes at low pH. XSelect Premier Columns use MaxPeak High Performance Surface hardware technology which significantly reduces unwanted analyte/surface interactions that can lead to poor peak shape and losses in signal intensity.