Quality controlled with peptide standards for the analysis of peptides, Waters ACQUITY Premier Peptide CSH, C18, 130Å, 1.7 µm particles contain a low and carefully-defined concentration of positive charges that yield comparatively excellent peak shape for peptides using either FA- or TFA-containing mobile phases. The fact that the performance of an ACQUITY Premier Peptide CSH, C18, 130Å, 1.7 µm Column exhibits little dependence on strong ion pairing agents makes it ideal for LC or LC-MS applications. This column is part of the MaxPeak Premier Class of Columns, which deliver the chromatographic performance expected from our particle technologies while increasing reproducibility, peak shape, and recovery for metal-sensitive analytes. such as phosphorylated peptides. The unique column design includes a fully integrated and easily replaceable 5mm pre-column that serves to protect and extend the life of the full-length analytical column, but adds no dispersion and has no impact on the resolution of your analytical separations. VanGuard FIT Cartridge replacements contain the same qualified sorbent as the analytical column and can easily be replaced.