Purospher® STAR RP-8 endcapped HPLC columns are less hydrophobic than Purospher® STAR RP-18 endcapped, hence analytes typically elute faster on the C8 phase. This results in enhanced selectivity for positional isomers, and excellent peak symmetry for strongly basic and polar compounds. Purospher® STAR RP-8 endcapped is based on high-purity silica with virtually perfect surface coverage. This ensures the highest efficiency in terms of the number of theoretical plates, and outstanding stability from pH 1.5 to 10.5.