Chiral HPLC Columns

Daicel's chiral HPLC columns are the most widely used chiral chromatography products in the world. Because of their exceptionally high durability, high power capacity, versatility and excellent separation performance, they are used primarily in HPLC as well as supercritical fluid chromatography (SFC). In addition, chiral stationary phases (CSPs) have become the first choice for enatiomer analysis and separation of chiral substances. The columns are available in a wide variety of configurations. To find the column you need more quickly and easily, use the filter options on the left or our HPLC column configurator.

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Product Image of HPLC Column CHIRALPAK IG-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IG-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC87S84
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK IG-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IG-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC87S83
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK IG-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IG-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC87S82
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Column CHIRALPAK® IG-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IG-3, 250 x 4,6 mm, 3 µm
Item number: DAIC87525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IG-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IG-3, 150 x 4,6 mm, 3 µm
Item number: DAIC87524
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IG-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC87511
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK® IG, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IG, 250 x 4,6 mm, 5 µm
Item number: DAIC87325
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IG, 150 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IG, 150 x 4,6 mm, 5 µm
Item number: DAIC87324
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IG, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IG, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC87311
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK IF-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IF-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC86S84
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK IF-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IF-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC86S83
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK IF-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IF-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC86S82
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Column CHIRALPAK® IF-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IF-3, 250 x 4,6 mm, 3 µm
Item number: DAIC86525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IF-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IF-3, 150 x 4,6 mm, 3 µm
Item number: DAIC86524
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IF-3, 100 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IF-3, 100 x 4,6 mm, 3 µm
Item number: DAIC86523
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK® IF-3, 50 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IF-3, 50 x 4,6 mm, 3 µm
Item number: DAIC86522
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IF-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IF-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC86511
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK® IF, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IF, 250 x 4,6 mm, 5 µm
Item number: DAIC86325
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IF, 150 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IF, 150 x 4,6 mm, 5 µm
Item number: DAIC86324
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Guard Cartridge CHIRALPAK IF, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK IF, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC86311
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK IE-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IE-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC85S84
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK IE-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IE-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC85S83
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK IE-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IE-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC85S82
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Column CHIRALPAK® IE-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IE-3, 250 x 4,6 mm, 3 µm
Item number: DAIC85525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IE-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IE-3, 150 x 4,6 mm, 3 µm
Item number: DAIC85524
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IE-3, 100 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IE-3, 100 x 4,6 mm, 3 µm
Item number: DAIC85523
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK® IE-3, 50 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IE-3, 50 x 4,6 mm, 3 µm
Item number: DAIC85522
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IE-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IE-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC85511
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK® IE, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IE, 250 x 4,6 mm, 5 µm
Item number: DAIC85325
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IE, 150 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® IE, 150 x 4,6 mm, 5 µm
Item number: DAIC85324
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Guard Cartridge CHIRALPAK® IE, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® IE, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC85311
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK ID-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK ID-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC84S84
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK ID-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK ID-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC84S83
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK ID-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK ID-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC84S82
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Column CHIRALPAK® ID-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® ID-3, 250 x 4,6 mm, 3 µm
Item number: DAIC84525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® ID-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® ID-3, 150 x 4,6 mm, 3 µm
Item number: DAIC84524
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® ID-3, 100 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® ID-3, 100 x 4,6 mm, 3 µm
Item number: DAIC84523
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK® ID-3, 50 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® ID-3, 50 x 4,6 mm, 3 µm
Item number: DAIC84522
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Guard Cartridge CHIRALPAK® ID-3, 10 x 4 mm, 3 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® ID-3, 10 x 4 mm, 3 µm, 3 pc/pak
Item number: DAIC84511
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK® ID, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® ID, 250 x 4,6 mm, 5 µm
Item number: DAIC84325
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® ID, 150 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® ID, 150 x 4,6 mm, 5 µm
Item number: DAIC84324
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Guard Cartridge CHIRALPAK® ID, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALPAK® ID, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC84311
Brand: Chiral

In stock

€390.00
Product Image of HPLC Column CHIRALPAK IC-U, 100 x 3 mm, sub-2 µm
HPLC Column CHIRALPAK IC-U, 100 x 3 mm, sub-2 µm
Item number: DAIC83U83
Brand: Chiral

In stock

€1,850.00
Product Image of HPLC Column CHIRALPAK IC-U, 50 x 3 mm, sub-2 µm
HPLC Column CHIRALPAK IC-U, 50 x 3 mm, sub-2 µm
Item number: DAIC83U82
Brand: Chiral

In stock

€1,350.00
Product Image of HPLC Column CHIRALPAK IC-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IC-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC83S84
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK IC-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IC-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC83S83
Brand: Chiral

In stock

€1,490.00
Product Image of HPLC Column CHIRALPAK IC-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALPAK IC-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC83S82
Brand: Chiral

In stock

€1,090.00
Product Image of HPLC Column CHIRALPAK® IC-3, 250 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IC-3, 250 x 4,6 mm, 3 µm
Item number: DAIC83525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IC-3, 150 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IC-3, 150 x 4,6 mm, 3 µm
Item number: DAIC83524
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK® IC-3, 100 x 4,6 mm, 3 µm
HPLC Column CHIRALPAK® IC-3, 100 x 4,6 mm, 3 µm
Item number: DAIC83523
Brand: Chiral

In stock

€1,490.00

Immobilised Chiralpak

Immobilised Chiralpak HPLC and SFC columns are packed with new Chiral Stationary Phases - consisting of a silica support onto which the polymeric chiral selector (polysaccharide derivatives) has been immobilised. Immobilisation of the polysaccharide derivatives on a matrix is an excellent approach to provide universal solvent compatibility on these highly selective Chiral Stationary Phases. This broadens the range of solvents to be used as mobile phases, thereby introducing new selectivity profiles, improved productivity and robustness in use.

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm 
Chiralpak IA 3, 5  Chiralpak IB SFC
Chiralpak IA SFC Chiralpak IC 3, 5 
Chiralpak IB 3, 5  Chiralpak IC SFC


Coated Chiralpak

The predecessors to the new generation of immobilised columns, traditional CHIRALPAK and CHIRALCEL coated polysaccharide Chiral Stationary Phases are made with a spherical high quality silica support onto which the polymeric chiral selector (amylose or cellulose derivatives) is physically coated. Due to the coated nature of these chiral supports, solvents should be carefully selected.

Phase
 
Particle Size
in µm
Phase
 
Particle Size
in µm
Chiralpak AD 3, 10 Chiralpak AS 3, 10
Chiralpak AD-H 5 Chiralpak AS-H 5
Chiralpak AZ 3 Chiralpak AY 3
Chiralpak AZ-H 5 Chiralpak AY-H


Coated Chiralcel

The predecessors to the new generation of immobilised columns, traditional CHIRALPAK and CHIRALCEL coated polysaccharide Chiral Stationary Phases are made with a spherical high quality silica support onto which the polymeric chiral selector (amylose or cellulose derivatives) is physically coated. Due to the coated nature of these chiral supports, solvents should be carefully selected.

Phase
 
Particle Size
in µm
Phase
 
Particle Size
in µm 
Chiralcel OA 10 Chiralcel OF 10 
Chiralcel OB  10  Chiralcel OG 10
Chiralcel OB-H Chiralcel OJ  3, 10 
Chiralcel OC  10  Chiralcel OJ-H 5
Chiralcel OC-H Chiralcel OK 10
Chiralcel OD  3, 10 Chiralcel OZ  3
Chiralcel OD-H Chiralcel OZ-H 5


Reverse Phase Chiralpak

CHIRALPAK® -3R & [-RH] & CHIRALCEL® -R & [-RH] have been developed by DAICEL as the reverse phase versions of CHIRALPAK® AD-H, AS-H, AY-H, AZ-H & CHIRALCEL® OD-H, OJ-H, OZ-H (Columns which have the widest applicability in normal phase mode). They have the same coated chiral selector as found in the normal phase stationary phases, but are coated to a hydrophobic high quality silica support.

Phase
 
Particle Size
in µm
Phase
 
Particle Size
in µm 
Chiralpak AD-3R Chiralpak AS-RH
Chiralpak AD-RH Chiralpak AY-3R
Chiralpak AS-3R 3 Chiralpak AZ-3R


Reverse Phase Chiralcel

CHIRALPAK® -3R & [-RH] & CHIRALCEL® -R & [-RH] have been developed by DAICEL as the reverse phase versions of CHIRALPAK® AD-H, AS-H, AY-H, AZ-H & CHIRALCEL® OD-H, OJ-H, OZ-H (Columns which have the widest applicability in normal phase mode). They have the same coated chiral selector as found in the normal phase stationary phases, but are coated to a hydrophobic high quality silica support.

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm
Chiralcel OD-3R Chiralcel OJ-3R
Chiralcel OD-RH Chiralcel OJ-RH
Chiralcel OD-R 10  Chiralcel OZ-3R


Chiralpak

These two phases, QD-AX and QN-AX, are based on two complementary stereoisomeric quinine (qN) and quinidine (qD) derivatives. Due to their pseudo enantiomeric character they usually reveal reversed elution order for opposite enantiomers.
The Chiral Stationary Phases, WH and MA(+), in these columns are made of amino acids and its derivatives coated bonded to silica supports (with a particle size of 10 μm for WH and 3 μm for MA(+)). Since these columns are ligand-exchange type columns, the standard mobile phase to use is an aqueous solution of CuSO4 (0.1 to 2mM). These columns can tolerate organic modifiers such as Methanol and Acetonitrile according specifications in the instruction manual. 

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm
Chiralpak QD-AX Chiralpak WH 10 
Chiralpak QN-AX Chiralpak MA(+)


Crownpak

These columns contain a chiral crown ether as a chiral selector, which is coated onto a 5 μm support. Acidic mobile phases such as Perchloric acid pH 1 to 2, are used to operate these columns under standard conditions. Note that to shorten the retention time of hydrophobic samples, the addition of Methanol (15% maximum v/v) has been shown to be effective. These columns are the reference columns for achieving amino acid separations, with the advantage the elution order of the enantiomers can be reversed when necessary (CR(-) column gives the reversed elution order compared to CR(+) column).

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm
Crownpak CR(+) 5 Crownpak CR(-) 5


Chromtech Chiral

These protein-based columns are suitable for several types of compounds; basic compounds can be separated on both CHIRAL-AGP and CHIRAL-CBH, acidic and neutral compounds can be separated on both CHIRAL-AGP and CHIRAL-HSA. However, as CHIRAL-AGP is a column with an extremely broad applicability, this column should be chosen first, if the analyte has not been separated on any of the columns.

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm
Chromtech AGP 5 Chromtech HSA
Chromtech CBH