Chiral HPLC Columns

Daicel's chiral HPLC columns are the most widely used chiral chromatography products in the world. Because of their exceptionally high durability, high power capacity, versatility and excellent separation performance, they are used primarily in HPLC as well as supercritical fluid chromatography (SFC). In addition, chiral stationary phases (CSPs) have become the first choice for enatiomer analysis and separation of chiral substances. The columns are available in a wide variety of configurations. To find the column you need more quickly and easily, use the filter options on the left or our HPLC column configurator.

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Product Image of HPLC Column CHIRALPAK® AD-H, 250 x 4,6 mm, 5 µm
HPLC Column CHIRALPAK® AD-H, 250 x 4,6 mm, 5 µm
Item number: DAIC19325
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALPAK AGP, 100 x 4 mm, 5 µm
HPLC Column CHIRALPAK AGP, 100 x 4 mm, 5 µm
Item number: DAIC30713
Brand: Chiral

In stock

€1,235.00 €1,300.00
Product Image of HPLC Column CHIRALCEL® OD, 250 x 4,6 mm, 10 µm
HPLC Column CHIRALCEL® OD, 250 x 4,6 mm, 10 µm
Item number: DAIC14025
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALPAK AD, 250 x 4.6 mm, 10 µm
HPLC Column CHIRALPAK AD, 250 x 4.6 mm, 10 µm
Item number: DAIC19025
Brand: Chiral

In stock

€1,738.50 €1,830.00
Product Image of HPLC Column CHIRALCEL OD-R, 250 x 4.6 mm, 10 µm
HPLC Column CHIRALCEL OD-R, 250 x 4.6 mm, 10 µm
Item number: DAIC14625
Brand: Chiral

In stock

€1,830.00
Product Image of HPLC Guard Column CROWNPAK CR, 10 x 4 mm, 5 µm
HPLC Guard Column CROWNPAK CR, 10 x 4 mm, 5 µm
Item number: DAIC27711
Brand: Chiral

In stock

€290.00
Product Image of HPLC column CROWNPAK CR(+), 150 x 4 mm, 5 µm
HPLC column CROWNPAK CR(+), 150 x 4 mm, 5 µm
Item number: DAIC27714
Brand: Chiral

In stock

€1,830.00
Product Image of HPLC column CROWNPAK CR(-), 150 x 4 mm, 5 µm
HPLC column CROWNPAK CR(-), 150 x 4 mm, 5 µm
Item number: DAIC28714
Brand: Chiral

In stock

€1,830.00
Product Image of HPLC Guard CHIRALPAK AGP, 10 x 4 mm, 5 µm, 2 pc/pak
HPLC Guard CHIRALPAK AGP, 10 x 4 mm, 5 µm, 2 pc/pak
Item number: DAIC30711
Brand: Chiral

In stock

€256.50 €270.00
Product Image of HPLC column CHIRALPAK AGP, 150 x 4 mm, 5 µm
HPLC column CHIRALPAK AGP, 150 x 4 mm, 5 µm
Item number: DAIC30714
Brand: Chiral

In stock

€1,619.75 €1,705.00
Product Image of HPLC column CHIRALPAK ZWIX(+), 250 x 4 mm, 3 µm
HPLC column CHIRALPAK ZWIX(+), 250 x 4 mm, 3 µm
Item number: DAIC51515
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC column CROWNPAK CR-I(+), 150 x 3 mm, 5 µm
HPLC column CROWNPAK CR-I(+), 150 x 3 mm, 5 µm
Item number: DAIC53784
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC column CHIRALPAK IA, 250 x 4.6 mm, 5 µm
HPLC column CHIRALPAK IA, 250 x 4.6 mm, 5 µm
Item number: DAIC80325
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC column CHIRALPAK IA, 250 x10 mm, 5 µm, Semi-Prep
HPLC column CHIRALPAK IA, 250 x10 mm, 5 µm, Semi-Prep
Item number: DAIC80335
Brand: Chiral
€5,700.00
Product Image of HPLC column CHIRALPAK IA-3, 250 x 4.6 mm, 3 µm
HPLC column CHIRALPAK IA-3, 250 x 4.6 mm, 3 µm
Item number: DAIC80525
Brand: Chiral

In stock

€1,860.00
Product Image of HPLC Column CHIRALPAK IA-U, 50 x 3 mm, sub-2 µm
HPLC Column CHIRALPAK IA-U, 50 x 3 mm, sub-2 µm
Item number: DAIC80U82
Brand: Chiral

In stock

€1,350.00
Product Image of HPLC column CHIRALPAK AY-H, 250 x 20 mm, 5 µm, Semi-Prep
HPLC column CHIRALPAK AY-H, 250 x 20 mm, 5 µm, Semi-Prep
Item number: DAIC47345
Brand: Chiral
€9,245.00
Product Image of HPLC Guard Column CHIRALCEL OA, 50 x 4.6 mm, 10 µm
HPLC Guard Column CHIRALCEL OA, 50 x 4.6 mm, 10 µm
Item number: DAIC11022
Brand: Chiral
€600.00
Product Image of HPLC Column CHIRALCEL OA, 250 x 4.6 mm, 10 µm
HPLC Column CHIRALCEL OA, 250 x 4.6 mm, 10 µm
Item number: DAIC11025
Brand: Chiral
€1,830.00
Product Image of HPLC Guard Column CHIRALCEL OB, 50 x 4.6 mm, 10 µm
HPLC Guard Column CHIRALCEL OB, 50 x 4.6 mm, 10 µm
Item number: DAIC12022
Brand: Chiral
€600.00
Product Image of HPLC Column CHIRALCEL OB, 250 x 4.6 mm, 10 µm
HPLC Column CHIRALCEL OB, 250 x 4.6 mm, 10 µm
Item number: DAIC12025
Brand: Chiral
€1,830.00
Product Image of HPLC Guard Cartridge CHIRALCEL OB-H, 10 x 4 mm, 5 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALCEL OB-H, 10 x 4 mm, 5 µm, 3 pc/pak
Item number: DAIC12311
Brand: Chiral

In stock

€380.00
Product Image of HPLC column CHIRALCEL OB-H, 150 x 4.6 mm, 5 µm
HPLC column CHIRALCEL OB-H, 150 x 4.6 mm, 5 µm
Item number: DAIC12324
Brand: Chiral

In stock

€1,830.00
Product Image of HPLC column CHIRALCEL OB-H, 250 x 4.6 mm, 5 µm
HPLC column CHIRALCEL OB-H, 250 x 4.6 mm, 5 µm
Item number: DAIC12325
Brand: Chiral

In stock

€1,830.00
Product Image of HPLC Guard Column CHIRALCEL OC, 50 x 4.6 mm, 10 µm
HPLC Guard Column CHIRALCEL OC, 50 x 4.6 mm, 10 µm
Item number: DAIC13022
Brand: Chiral
€600.00
Product Image of HPLC Column CHIRALCEL OC, 250 x 4.6 mm, 10 µm
HPLC Column CHIRALCEL OC, 250 x 4.6 mm, 10 µm
Item number: DAIC13025
Brand: Chiral
€1,830.00
Product Image of HPLC column CHIRALCEL OC-H, 250 x 4.6 mm, 5 µm
HPLC column CHIRALCEL OC-H, 250 x 4.6 mm, 5 µm
Item number: DAIC13325
Brand: Chiral

In stock

€1,830.00
Product Image of HPLC Column CHIRALCEL OD, 150 x 4.6 mm, 10 µm
HPLC Column CHIRALCEL OD, 150 x 4.6 mm, 10 µm
Item number: DAIC14024
Brand: Chiral
€1,830.00
Product Image of HPLC Guard CHIRALCEL OD, 50 x 10 mm, 10 µm, Semi-Prep
HPLC Guard CHIRALCEL OD, 50 x 10 mm, 10 µm, Semi-Prep
Item number: DAIC14032
Brand: Chiral
€910.00
Product Image of HPLC Column CHIRALCEL OD, 250 x10 mm, 10 µm, Semi-Prep
HPLC Column CHIRALCEL OD, 250 x10 mm, 10 µm, Semi-Prep
Item number: DAIC14035
Brand: Chiral
€4,925.00
Product Image of HPLC Guard CHIRALCEL OD, 50 x 20 mm, 10 µm, Semi-Prep
HPLC Guard CHIRALCEL OD, 50 x 20 mm, 10 µm, Semi-Prep
Item number: DAIC14042
Brand: Chiral
€1,730.00
Product Image of HPLC Column CHIRALCEL OD, 250 x 20 mm, 10 µm, Semi-Prep
HPLC Column CHIRALCEL OD, 250 x 20 mm, 10 µm, Semi-Prep
Item number: DAIC14045
Brand: Chiral
€9,245.00
Product Image of HPLC Guard Column CHIRALCEL OD-H, 50 x 4.6 mm, 5 µm, old number: DAIC14321
HPLC Guard Column CHIRALCEL OD-H, 50 x 4.6 mm, 5 µm, old number: DAIC14321
Item number: DAIC14322
Brand: Chiral
€1,060.00
Product Image of HPLC column CHIRALCEL OD-H, 250 x 10 mm, 5 µm, Semi-Prep
HPLC column CHIRALCEL OD-H, 250 x 10 mm, 5 µm, Semi-Prep
Item number: DAIC14335
Brand: Chiral
€4,925.00
Product Image of HPLC Guard CHIRALCEL OD-H, 20 x 10 mm, 5 µm, Semi-Prep
HPLC Guard CHIRALCEL OD-H, 20 x 10 mm, 5 µm, Semi-Prep
Item number: DAIC14337
Brand: Chiral
€1,400.00
Product Image of HPLC column CHIRALCEL OD-H, 250 x 20 mm, 5 µm, Semi-Prep
HPLC column CHIRALCEL OD-H, 250 x 20 mm, 5 µm, Semi-Prep
Item number: DAIC14345
Brand: Chiral
€9,245.00
Product Image of HPLC Column CHIRALCEL OD-H, 250 x 10 mm, 5 µm, SFC, Semi-Prep
HPLC Column CHIRALCEL OD-H, 250 x 10 mm, 5 µm, SFC, Semi-Prep
Item number: DAIC14435
Brand: Chiral
€4,925.00
Product Image of HPLC Column CHIRALCEL OD-H, 250 x 20 mm, 5 µm, SFC, Semi-Prep
HPLC Column CHIRALCEL OD-H, 250 x 20 mm, 5 µm, SFC, Semi-Prep
Item number: DAIC14445
Brand: Chiral
€9,245.00
Product Image of HPLC Guard Cartridge CHIRALCEL OD-R, 10 x 4 mm, 10 µm, 3 pc/pak
HPLC Guard Cartridge CHIRALCEL OD-R, 10 x 4 mm, 10 µm, 3 pc/pak
Item number: DAIC14611
Brand: Chiral

In stock

€380.00
Product Image of HPLC column CHIRALCEL OD-3R, 50 x 2.1 mm, 3 µm
HPLC column CHIRALCEL OD-3R, 50 x 2.1 mm, 3 µm
Item number: DAIC14892
Brand: Chiral
€1,060.00
Product Image of HPLC column CHIRALCEL OD-3R, 100 x 2.1 mm, 3 µm
HPLC column CHIRALCEL OD-3R, 100 x 2.1 mm, 3 µm
Item number: DAIC14893
Brand: Chiral
€1,445.00
Product Image of HPLC column CHIRALCEL OD-3R, 250 x 2.1 mm, 3 µm
HPLC column CHIRALCEL OD-3R, 250 x 2.1 mm, 3 µm
Item number: DAIC14895
Brand: Chiral
€1,830.00
Product Image of HPLC Column CHIRALCEL OD-3, 50 x 3 mm, 3 µm, SFC
HPLC Column CHIRALCEL OD-3, 50 x 3 mm, 3 µm, SFC
Item number: DAIC14S82
Brand: Chiral

In stock

€1,060.00
Product Image of HPLC Column CHIRALCEL OD-3, 100 x 3 mm, 3 µm, SFC
HPLC Column CHIRALCEL OD-3, 100 x 3 mm, 3 µm, SFC
Item number: DAIC14S83
Brand: Chiral

In stock

€1,445.00
Product Image of HPLC Column CHIRALCEL OD-3, 150 x 3 mm, 3 µm, SFC
HPLC Column CHIRALCEL OD-3, 150 x 3 mm, 3 µm, SFC
Item number: DAIC14S84
Brand: Chiral

In stock

€1,830.00
Product Image of HPLC Guard Column CHIRALCEL OG, 50 x 4.6 mm, 10 µm
HPLC Guard Column CHIRALCEL OG, 50 x 4.6 mm, 10 µm
Item number: DAIC16022
Brand: Chiral
€600.00
Product Image of HPLC Column CHIRALCEL OJ, 150 x 4.6 mm, 10 µm
HPLC Column CHIRALCEL OJ, 150 x 4.6 mm, 10 µm
Item number: DAIC17024
Brand: Chiral
€1,830.00
Product Image of HPLC Guard CHIRALCEL OJ, 50 x 10 mm, 10 µm, Semi-Prep
HPLC Guard CHIRALCEL OJ, 50 x 10 mm, 10 µm, Semi-Prep
Item number: DAIC17032
Brand: Chiral
€910.00
Product Image of HPLC Column CHIRALCEL OJ, 250 x 10 mm, 10 µm, Semi-Prep
HPLC Column CHIRALCEL OJ, 250 x 10 mm, 10 µm, Semi-Prep
Item number: DAIC17035
Brand: Chiral
€4,925.00
Product Image of HPLC Guard CHIRALCEL OJ, 50 x 20 mm, 10 µm, Semi-Prep
HPLC Guard CHIRALCEL OJ, 50 x 20 mm, 10 µm, Semi-Prep
Item number: DAIC17042
Brand: Chiral
€1,730.00

Immobilised Chiralpak

Immobilised Chiralpak HPLC and SFC columns are packed with new Chiral Stationary Phases - consisting of a silica support onto which the polymeric chiral selector (polysaccharide derivatives) has been immobilised. Immobilisation of the polysaccharide derivatives on a matrix is an excellent approach to provide universal solvent compatibility on these highly selective Chiral Stationary Phases. This broadens the range of solvents to be used as mobile phases, thereby introducing new selectivity profiles, improved productivity and robustness in use.

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm 
Chiralpak IA 3, 5  Chiralpak IB SFC
Chiralpak IA SFC Chiralpak IC 3, 5 
Chiralpak IB 3, 5  Chiralpak IC SFC


Coated Chiralpak

The predecessors to the new generation of immobilised columns, traditional CHIRALPAK and CHIRALCEL coated polysaccharide Chiral Stationary Phases are made with a spherical high quality silica support onto which the polymeric chiral selector (amylose or cellulose derivatives) is physically coated. Due to the coated nature of these chiral supports, solvents should be carefully selected.

Phase
 
Particle Size
in µm
Phase
 
Particle Size
in µm
Chiralpak AD 3, 10 Chiralpak AS 3, 10
Chiralpak AD-H 5 Chiralpak AS-H 5
Chiralpak AZ 3 Chiralpak AY 3
Chiralpak AZ-H 5 Chiralpak AY-H


Coated Chiralcel

The predecessors to the new generation of immobilised columns, traditional CHIRALPAK and CHIRALCEL coated polysaccharide Chiral Stationary Phases are made with a spherical high quality silica support onto which the polymeric chiral selector (amylose or cellulose derivatives) is physically coated. Due to the coated nature of these chiral supports, solvents should be carefully selected.

Phase
 
Particle Size
in µm
Phase
 
Particle Size
in µm 
Chiralcel OA 10 Chiralcel OF 10 
Chiralcel OB  10  Chiralcel OG 10
Chiralcel OB-H Chiralcel OJ  3, 10 
Chiralcel OC  10  Chiralcel OJ-H 5
Chiralcel OC-H Chiralcel OK 10
Chiralcel OD  3, 10 Chiralcel OZ  3
Chiralcel OD-H Chiralcel OZ-H 5


Reverse Phase Chiralpak

CHIRALPAK® -3R & [-RH] & CHIRALCEL® -R & [-RH] have been developed by DAICEL as the reverse phase versions of CHIRALPAK® AD-H, AS-H, AY-H, AZ-H & CHIRALCEL® OD-H, OJ-H, OZ-H (Columns which have the widest applicability in normal phase mode). They have the same coated chiral selector as found in the normal phase stationary phases, but are coated to a hydrophobic high quality silica support.

Phase
 
Particle Size
in µm
Phase
 
Particle Size
in µm 
Chiralpak AD-3R Chiralpak AS-RH
Chiralpak AD-RH Chiralpak AY-3R
Chiralpak AS-3R 3 Chiralpak AZ-3R


Reverse Phase Chiralcel

CHIRALPAK® -3R & [-RH] & CHIRALCEL® -R & [-RH] have been developed by DAICEL as the reverse phase versions of CHIRALPAK® AD-H, AS-H, AY-H, AZ-H & CHIRALCEL® OD-H, OJ-H, OZ-H (Columns which have the widest applicability in normal phase mode). They have the same coated chiral selector as found in the normal phase stationary phases, but are coated to a hydrophobic high quality silica support.

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm
Chiralcel OD-3R Chiralcel OJ-3R
Chiralcel OD-RH Chiralcel OJ-RH
Chiralcel OD-R 10  Chiralcel OZ-3R


Chiralpak

These two phases, QD-AX and QN-AX, are based on two complementary stereoisomeric quinine (qN) and quinidine (qD) derivatives. Due to their pseudo enantiomeric character they usually reveal reversed elution order for opposite enantiomers.
The Chiral Stationary Phases, WH and MA(+), in these columns are made of amino acids and its derivatives coated bonded to silica supports (with a particle size of 10 μm for WH and 3 μm for MA(+)). Since these columns are ligand-exchange type columns, the standard mobile phase to use is an aqueous solution of CuSO4 (0.1 to 2mM). These columns can tolerate organic modifiers such as Methanol and Acetonitrile according specifications in the instruction manual. 

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm
Chiralpak QD-AX Chiralpak WH 10 
Chiralpak QN-AX Chiralpak MA(+)


Crownpak

These columns contain a chiral crown ether as a chiral selector, which is coated onto a 5 μm support. Acidic mobile phases such as Perchloric acid pH 1 to 2, are used to operate these columns under standard conditions. Note that to shorten the retention time of hydrophobic samples, the addition of Methanol (15% maximum v/v) has been shown to be effective. These columns are the reference columns for achieving amino acid separations, with the advantage the elution order of the enantiomers can be reversed when necessary (CR(-) column gives the reversed elution order compared to CR(+) column).

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm
Crownpak CR(+) 5 Crownpak CR(-) 5


Chromtech Chiral

These protein-based columns are suitable for several types of compounds; basic compounds can be separated on both CHIRAL-AGP and CHIRAL-CBH, acidic and neutral compounds can be separated on both CHIRAL-AGP and CHIRAL-HSA. However, as CHIRAL-AGP is a column with an extremely broad applicability, this column should be chosen first, if the analyte has not been separated on any of the columns.

Phase
 
Particle Size
in µm 
Phase
 
Particle Size
in µm
Chromtech AGP 5 Chromtech HSA
Chromtech CBH