HPLC Guard Columns

Precolumns (guard columns) and precolumn cartridges for HPLC

Separation columns with modern solid phases are critical components of the HPLC system. Careful handling and protection against impurities is necessary to ensure optimum and consistent separation results. In order to extend the life of your HPLC columns, it is advisable to use guard columns. They are able to remove molecules which would form an irreversible bond with the material of the analytical column. Guard coloumns need to be changed on a regular basis. A good indication on when to change a precolumn is a gradual increase in the back pressure. For more information on the storage and maintenance of HPLC column, click here.

We carry a wide range of solid phase and stainless steel cartridges for HPLC and UHPLC.

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Product Image of Universal Reversed Phase (RP) PreColumn Cartridge 5x2mm for Columns with 2 mm ID, 5/PAK
Universal Reversed Phase (RP) PreColumn Cartridge 5x2mm for Columns with 2 mm ID, 5/PAK
Item number: AAVRP-500520-5
Brand: Altmann Analytik

In stock

€225.00
Product Image of Universal Reversed Phase (RP) PreColumn Cartridge 20x4mm for Columns with 3, 4 and 4,6 mm ID, 5/PAK
Universal Reversed Phase (RP) PreColumn Cartridge 20x4mm for Columns with 3, 4 and 4,6 mm ID, 5/PAK
Item number: AAVRP-201040-5
Brand: Altmann Analytik

In stock

€275.00
Product Image of HPLC Guard Column Nucleosil 100 C18, 5.0 µm, 4 x 10 mm, 5pc/PAK
HPLC Guard Column Nucleosil 100 C18, 5.0 µm, 4 x 10 mm, 5pc/PAK
Item number: AAVNS1C9-501040-5
Brand: Altmann Analytik

In stock

€185.63 €206.25
Product Image of HPLC Guard Column Holder indirect, 5 x 4 mm
HPLC Guard Column Holder indirect, 5 x 4 mm
Item number: AAHI-00540
Brand: Altmann Analytik

In stock

€113.40 €126.00
Product Image of HPLC Guard Column Holder indirect, 10 x 4,6 mm
HPLC Guard Column Holder indirect, 10 x 4,6 mm
Item number: AAHI-01046
Brand: Altmann Analytik

In stock

€118.80 €132.00
Product Image of HPLC Guard Column Holder indirect, 10 x 4 mm
HPLC Guard Column Holder indirect, 10 x 4 mm
Item number: AAHI-01040
Brand: Altmann Analytik

In stock

€118.80 €132.00
Product Image of HPLC Guard Column Holder indirect, 10 x 3 mm
HPLC Guard Column Holder indirect, 10 x 3 mm
Item number: AAHI-01030
Brand: Altmann Analytik

In stock

€118.80 €132.00
Product Image of HPLC Guard Column Reprosil Pur 120 C18-AQ, 3.0 µm, 2 x 5 mm, 5pc/PAK
HPLC Guard Column Reprosil Pur 120 C18-AQ, 3.0 µm, 2 x 5 mm, 5pc/PAK
Item number: AAVRSPU9Q-30520-5
Brand: Altmann Analytik
€135.00
Product Image of HPLC Guard Cartridges Eurospher C18 5µm, 10 x 4.0 mm, 5pc/PAK
HPLC Guard Cartridges Eurospher C18 5µm, 10 x 4.0 mm, 5pc/PAK
Item number: AANEUC9-501040-5
Brand: Altmann Analytik
€240.33
Product Image of HPLC Guard Column Reprosil Pur 120 C18-AQ, 5.0 µm, 4.6 x 10 mm, 5pc/PAK
HPLC Guard Column Reprosil Pur 120 C18-AQ, 5.0 µm, 4.6 x 10 mm, 5pc/PAK
Item number: AAVRSPU9Q-501046-5
Brand: Altmann Analytik
€150.00
Product Image of HPLC Guard Cartridge Spherisorb 80Å ODS-2 5µm 20x4.6mm, 5/PAK
HPLC Guard Cartridge Spherisorb 80Å ODS-2 5µm 20x4.6mm, 5/PAK
Item number: AAVSSO2-502046-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Ultrasep ES AP, 5,0 µm, 4 x 10 mm, 5 pc/PAK
HPLC Guard Column Ultrasep ES AP, 5,0 µm, 4 x 10 mm, 5 pc/PAK
Item number: AAVUSEAP-501040-5
Brand: Altmann Analytik
€140.00
Product Image of HPLC Guard Column Nucleosil 100 C18, 10.0 µm, 10x4.6mm, 5pc/PAK
HPLC Guard Column Nucleosil 100 C18, 10.0 µm, 10x4.6mm, 5pc/PAK
Item number: AAVNS1C9-1001046-5
Brand: Altmann Analytik
€200.00
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 4.6 x 5 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 4.6 x 5 mm, 5pc/PAK
Item number: AAVSUS6-40546-5
Brand: Altmann Analytik
€373.33
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 4 x 5 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 4 x 5 mm, 5pc/PAK
Item number: AAVSUS6-40540-5
Brand: Altmann Analytik
€240.33
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 2 x 5 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 2 x 5 mm, 5pc/PAK
Item number: AAVSUS6-40520-5
Brand: Altmann Analytik
€240.33
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 4.6 x 20 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 4.6 x 20 mm, 5pc/PAK
Item number: AAVSUS6-402046-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 4 x 20 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 4 x 20 mm, 5pc/PAK
Item number: AAVSUS6-402040-5
Brand: Altmann Analytik
€290.50
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 2 x 20 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 2 x 20 mm, 5pc/PAK
Item number: AAVSUS6-402020-5
Brand: Altmann Analytik
€290.50
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 4.6 x 10 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 4.6 x 10 mm, 5pc/PAK
Item number: AAVSUS6-401046-5
Brand: Altmann Analytik
€400.00
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 4 x 10 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 4 x 10 mm, 5pc/PAK
Item number: AAVSUS6-401040-5
Brand: Altmann Analytik
€240.33
Product Image of HPLC Guard Column Superspher Si 60, 4.0 µm, 2 x 10 mm, 5pc/PAK
HPLC Guard Column Superspher Si 60, 4.0 µm, 2 x 10 mm, 5pc/PAK
Item number: AAVSUS6-401020-5
Brand: Altmann Analytik
€240.33
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 4.6 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 4.6 x 5 mm, 5pc/PAK
Item number: AAVSSSX-50546-5
Brand: Altmann Analytik
€373.33
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 4 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 4 x 5 mm, 5pc/PAK
Item number: AAVSSSX-50540-5
Brand: Altmann Analytik
€360.00
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 3 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 3 x 5 mm, 5pc/PAK
Item number: AAVSSSX-50530-5
Brand: Altmann Analytik
€360.00
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 2 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 2 x 5 mm, 5pc/PAK
Item number: AAVSSSX-50520-5
Brand: Altmann Analytik
€360.00
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 4.6 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 4.6 x 20 mm, 5pc/PAK
Item number: AAVSSSX-502046-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 4 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 4 x 20 mm, 5pc/PAK
Item number: AAVSSSX-502040-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 3 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 3 x 20 mm, 5pc/PAK
Item number: AAVSSSX-502030-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 2 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 2 x 20 mm, 5pc/PAK
Item number: AAVSSSX-502020-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 4.6 x 10 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 4.6 x 10 mm, 5pc/PAK
Item number: AAVSSSX-501046-5
Brand: Altmann Analytik
€400.00
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 4 x 10 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 4 x 10 mm, 5pc/PAK
Item number: AAVSSSX-501040-5
Brand: Altmann Analytik
€373.33
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 3 x 10 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 3 x 10 mm, 5pc/PAK
Item number: AAVSSSX-501030-5
Brand: Altmann Analytik
€373.33
Product Image of HPLC Guard Column Spherisorb SAX, 5.0 µm, 2 x 10 mm, 5pc/PAK
HPLC Guard Column Spherisorb SAX, 5.0 µm, 2 x 10 mm, 5pc/PAK
Item number: AAVSSSX-501020-5
Brand: Altmann Analytik
€386.67
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 4.6 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 4.6 x 5 mm, 5pc/PAK
Item number: AAVSSS-50546-5
Brand: Altmann Analytik
€373.33
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 4 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 4 x 5 mm, 5pc/PAK
Item number: AAVSSS-50540-5
Brand: Altmann Analytik
€215.83
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 2 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 2 x 5 mm, 5pc/PAK
Item number: AAVSSS-50520-5
Brand: Altmann Analytik
€360.00
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 4.6 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 4.6 x 20 mm, 5pc/PAK
Item number: AAVSSS-502046-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 4 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 4 x 20 mm, 5pc/PAK
Item number: AAVSSS-502040-5
Brand: Altmann Analytik
€262.50
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 2 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 2 x 20 mm, 5pc/PAK
Item number: AAVSSS-502020-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 4.6 x 10 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 4.6 x 10 mm, 5pc/PAK
Item number: AAVSSS-501046-5
Brand: Altmann Analytik
€400.00
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 4 x 10 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 4 x 10 mm, 5pc/PAK
Item number: AAVSSS-501040-5
Brand: Altmann Analytik
€215.83
Product Image of HPLC Guard Column Spherisorb Si, 5.0 µm, 2 x 10 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 5.0 µm, 2 x 10 mm, 5pc/PAK
Item number: AAVSSS-501020-5
Brand: Altmann Analytik
€386.67
Product Image of HPLC Guard Column Spherisorb Si, 3.0 µm, 4.6 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 3.0 µm, 4.6 x 5 mm, 5pc/PAK
Item number: AAVSSS-30546-5
Brand: Altmann Analytik
€373.33
Product Image of HPLC Guard Column Spherisorb Si, 3.0 µm, 4 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 3.0 µm, 4 x 5 mm, 5pc/PAK
Item number: AAVSSS-30540-5
Brand: Altmann Analytik
€290.42
Product Image of HPLC Guard Column Spherisorb Si, 3.0 µm, 2 x 5 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 3.0 µm, 2 x 5 mm, 5pc/PAK
Item number: AAVSSS-30520-5
Brand: Altmann Analytik
€360.00
Product Image of HPLC Guard Column Spherisorb Si, 3.0 µm, 4.6 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 3.0 µm, 4.6 x 20 mm, 5pc/PAK
Item number: AAVSSS-302046-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Spherisorb Si, 3.0 µm, 4 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 3.0 µm, 4 x 20 mm, 5pc/PAK
Item number: AAVSSS-302040-5
Brand: Altmann Analytik
€417.92
Product Image of HPLC Guard Column Spherisorb Si, 3.0 µm, 2 x 20 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 3.0 µm, 2 x 20 mm, 5pc/PAK
Item number: AAVSSS-302020-5
Brand: Altmann Analytik
€440.00
Product Image of HPLC Guard Column Spherisorb Si, 3.0 µm, 4.6 x 10 mm, 5pc/PAK
HPLC Guard Column Spherisorb Si, 3.0 µm, 4.6 x 10 mm, 5pc/PAK
Item number: AAVSSS-301046-5
Brand: Altmann Analytik
€400.00

If you want to protect your column from contamination by connecting a precolumn cartridge upstream, you always need a precolumn holder as well. At Analytics-Shop you will find HPLC precolumns from all well-known manufacturers, from Agilent Technologies and Chiral to Macherey-Nagel, Merck, Thermo Scientific, Waters and Whatman. High quality and at the same time very affordable alternatives of precolumns and columns are products of our house brand Altmann Analytik.

Indirect pre-column holders are compatible with the common columns of all manufacturers. For this you need an additional column connector as an intermediate piece between column and pre-column holder. The following graphic shows the connection possibilities if you need a pre-column for an HPLC column (column connectors must be ordered separately):

 

In general, the length of the precolumn should not exceed 10 percent of the column. We therefore recommend

- for columns with length up to 50 mm: precolumns with length 5 mm
- for columns with length from 60 mm to 199 mm: precolumns with length 10 mm
- for columns with length of 200 mm and larger: precolumns with length 20 mm